ID A0A0K9GCF4_9BACI Unreviewed; 383 AA.
AC A0A0K9GCF4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:KMY44363.1};
GN ORFNames=AC622_08960 {ECO:0000313|EMBL:KMY44363.1};
OS Bacillus sp. FJAT-27916.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1679169 {ECO:0000313|EMBL:KMY44363.1, ECO:0000313|Proteomes:UP000036953};
RN [1] {ECO:0000313|Proteomes:UP000036953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJAT-27916 {ECO:0000313|Proteomes:UP000036953};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Chen Z., Che J., Ge C., Shi H.,
RA Pan Z., Liu X.;
RT "Genome sequencing project for genomic taxonomy and phylogenomics of
RT Bacillus-like bacteria.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMY44363.1}.
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DR EMBL; LFZV01000001; KMY44363.1; -; Genomic_DNA.
DR RefSeq; WP_049670763.1; NZ_LFZV01000001.1.
DR AlphaFoldDB; A0A0K9GCF4; -.
DR STRING; 1679169.AC622_08960; -.
DR PATRIC; fig|1679169.3.peg.1923; -.
DR OrthoDB; 9764892at2; -.
DR Proteomes; UP000036953; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000036953};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:KMY44363.1}.
FT DOMAIN 5..252
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 260..381
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 89
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 338
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 368
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 383 AA; 41432 MW; 1CBC5B7CA25E1F1E CRC64;
MREAVIVEAV RTPVGKRKGV FKDIRPDDLL SYALKEVVKR SGILAELVED VIIGCVSQVE
EQGINIARSA ALMADFPVKV PGTTIDRQCG SSQQAIHFAA QAILSGDMDI VIAGGVESMT
RVPMGSTRKE SRPSKELSSR YELINQGLSA ERIAEKWGYD RQQLDEFSLM SHQRAINAQN
EGRFDREIMP IEVIEEDGTK TLVTQDEGPR RGTSLEKLGT LPAAFKEDGI IHAGNASQMS
DGAAVVLVMS KEKALELGLK PRFKLVARTV VGSDPTLMLT GPIEATRMVL EKAGLTIEDI
DLYEVNEAFA PVPLAWLDDI GANPEKLNVN GGAIALGHPL GASGARVMIT LMHELERTEG
KYGLQAICEG AGMANATIIE RLT
//
