ID A0A0K9NNN2_ZOSMR Unreviewed; 713 AA.
AC A0A0K9NNN2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0000259|SMART:SM01340};
GN ORFNames=ZOSMA_83G00490 {ECO:0000313|EMBL:KMZ57672.1};
OS Zostera marina (Eelgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Zosteraceae; Zostera.
OX NCBI_TaxID=29655 {ECO:0000313|EMBL:KMZ57672.1, ECO:0000313|Proteomes:UP000036987};
RN [1] {ECO:0000313|Proteomes:UP000036987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Finnish {ECO:0000313|Proteomes:UP000036987};
RX PubMed=26814964; DOI=10.1038/nature16548;
RA Olsen J.L., Rouze P., Verhelst B., Lin Y.-C., Bayer T., Collen J.,
RA Dattolo E., De Paoli E., Dittami S., Maumus F., Michel G., Kersting A.,
RA Lauritano C., Lohaus R., Toepel M., Tonon T., Vanneste K., Amirebrahimi M.,
RA Brakel J., Bostroem C., Chovatia M., Grimwood J., Jenkins J.W.,
RA Jueterbock A., Mraz A., Stam W.T., Tice H., Bornberg-Bauer E., Green P.J.,
RA Pearson G.A., Procaccini G., Duarte C.M., Schmutz J., Reusch T.B.H.,
RA Van de Peer Y.;
RT "The genome of the seagrass Zostera marina reveals angiosperm adaptation to
RT the sea.";
RL Nature 530:331-335(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMZ57672.1}.
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DR EMBL; LFYR01002038; KMZ57672.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K9NNN2; -.
DR STRING; 29655.A0A0K9NNN2; -.
DR OMA; ANYHVKK; -.
DR OrthoDB; 5475669at2759; -.
DR Proteomes; UP000036987; Unassembled WGS sequence.
DR GO; GO:0032389; C:MutLalpha complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IBA:GO_Central.
DR CDD; cd16926; HATPase_MutL-MLH-PMS-like; 1.
DR CDD; cd03483; MutL_Trans_MLH1; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032189; Mlh1_C.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF12; DNA MISMATCH REPAIR PROTEIN MLH1; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF16413; Mlh1_C; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000036987}.
FT DOMAIN 225..347
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT REGION 376..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 713 AA; 80403 MW; 193DF71CC16E9AD5 CRC64;
MEVSEILEGS EKIIPKIRRL DQSVVNRIAA GEVVQRPVSA VKELVENSLD AGSTSISVVV
KDGGMKLIQV TDNGHGIRFD DLPILCERHT TSKLSTYEDL QTVKSMGFRG EALASMTYVG
HVTVTTITEG RLHGYRVSYR DGVMEHDPKP CAAVKGTQIT VENLFYNMLA RKKSLQNSND
DYTKIVDLIS RFAIHNIHVS FSCRKHGANR ADVHTIAACT KFDSIRSVFG VSVSHDILEI
TASDDNPDRS VFKLNGFVSN ANYIAKKTTM VLFINDRLVE CTALKRAIEV VYSATLPKAS
KPFIYMTIQL PHEHVDVNIH PTKREVSFLN QENIISTIQN AVETKLMNSN SILSKEIAVN
SQSSGQKTPK VPVNKMVRTD SKDPAGRLHS YWQDKHASQD DKRSELSCVR VAVRQRRNPK
KSADLTSLHE LLNEIDQNTH SSLLDIVKNC TYVGMADDIF ALIQHDTRLY LVNVVNVSEE
LMYQQVLRRF AHFNAIQLSD PAPIHELIMM ALSEENAECE DVESEDFNKI AEMNTELLKQ
KAELLQEYFG IDIDQKGFLL KLPVILDQYT PNMDRVPEFM LTLGNDVEWD DEKKCFQTIS
AAIGNFYAMQ PPILPNPSGD GAQFYKNTEA PDNRQNKDTD ANMIDDISEK NGTTDQKMVS
EAETEWAQRE WTIQHVLIPS MRLFFKPPIF MAGNGTFVQV ASLEKLYKIF ERC
//
