ID A0A0K9PZE2_ZOSMR Unreviewed; 276 AA.
AC A0A0K9PZE2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 22-FEB-2023, entry version 28.
DE RecName: Full=Transcription initiation factor IIE subunit beta {ECO:0000256|PIRNR:PIRNR016398};
GN ORFNames=ZOSMA_132G00520 {ECO:0000313|EMBL:KMZ74284.1};
OS Zostera marina (Eelgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Zosteraceae; Zostera.
OX NCBI_TaxID=29655 {ECO:0000313|EMBL:KMZ74284.1, ECO:0000313|Proteomes:UP000036987};
RN [1] {ECO:0000313|Proteomes:UP000036987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Finnish {ECO:0000313|Proteomes:UP000036987};
RX PubMed=26814964; DOI=10.1038/nature16548;
RA Olsen J.L., Rouze P., Verhelst B., Lin Y.-C., Bayer T., Collen J.,
RA Dattolo E., De Paoli E., Dittami S., Maumus F., Michel G., Kersting A.,
RA Lauritano C., Lohaus R., Toepel M., Tonon T., Vanneste K., Amirebrahimi M.,
RA Brakel J., Bostroem C., Chovatia M., Grimwood J., Jenkins J.W.,
RA Jueterbock A., Mraz A., Stam W.T., Tice H., Bornberg-Bauer E., Green P.J.,
RA Pearson G.A., Procaccini G., Duarte C.M., Schmutz J., Reusch T.B.H.,
RA Van de Peer Y.;
RT "The genome of the seagrass Zostera marina reveals angiosperm adaptation to
RT the sea.";
RL Nature 530:331-335(2016).
CC -!- FUNCTION: Recruits TFIIH to the initiation complex and stimulates the
CC RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase
CC activities of TFIIH. Both TFIIH and TFIIE are required for promoter
CC clearance by RNA polymerase. {ECO:0000256|ARBA:ARBA00025581,
CC ECO:0000256|PIRNR:PIRNR016398}.
CC -!- SUBUNIT: Tetramer of two alpha and two beta chains.
CC {ECO:0000256|PIRNR:PIRNR016398}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR016398}.
CC -!- SIMILARITY: Belongs to the TFIIE beta subunit family.
CC {ECO:0000256|PIRNR:PIRNR016398}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMZ74284.1}.
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DR EMBL; LFYR01000379; KMZ74284.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K9PZE2; -.
DR STRING; 29655.A0A0K9PZE2; -.
DR OrthoDB; 453982at2759; -.
DR Proteomes; UP000036987; Unassembled WGS sequence.
DR GO; GO:0005673; C:transcription factor TFIIE complex; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IBA:GO_Central.
DR InterPro; IPR040501; TFA2_Winged_2.
DR InterPro; IPR016656; TFIIE-bsu.
DR InterPro; IPR003166; TFIIE_bsu_DNA-bd.
DR PANTHER; PTHR12716:SF8; TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA; 1.
DR PANTHER; PTHR12716; TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT; 1.
DR Pfam; PF18121; TFA2_Winged_2; 1.
DR Pfam; PF02186; TFIIE_beta; 1.
DR PIRSF; PIRSF016398; TFIIE-beta; 1.
DR PROSITE; PS51351; TFIIE_BETA_C; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR016398};
KW Initiation factor {ECO:0000313|EMBL:KMZ74284.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR016398};
KW Protein biosynthesis {ECO:0000313|EMBL:KMZ74284.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000036987};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR016398};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR016398}.
FT DOMAIN 58..133
FT /note="TFIIE beta"
FT /evidence="ECO:0000259|PROSITE:PS51351"
FT REGION 22..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 276 AA; 31675 MW; FB7772D268333F50 CRC64;
MSNLEESLNK FKQQQAKCQT VLKNTKQQRP NNGPSNPTKY SAPAKPQAAI KFSYDTERLQ
QVSTIRKSPV GAQIKRVIDL LLETRQAYTA EQINDAIYVD INGNHAVFES LKNNLKVKYN
GKYFSYKPKH DLKDKTQLLE LITKCPEGLL VVDVKDSYTS VLDDLKTLKA EGRVWILSNV
DSQEDIVYPN DPKSNIKSEF ALKKLFREIK LPTDMLLIEK DLQNIGMKPF TDTMKRRETV
QVVPAPTNPN QKKKKKREIT KRTKLTNAHL PELFQI
//
