ID A0A0K9Q3R3_ZOSMR Unreviewed; 2934 AA.
AC A0A0K9Q3R3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=glutathione transferase {ECO:0000256|ARBA:ARBA00012452};
DE EC=2.5.1.18 {ECO:0000256|ARBA:ARBA00012452};
GN ORFNames=ZOSMA_109G00190 {ECO:0000313|EMBL:KMZ75928.1};
OS Zostera marina (Eelgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Zosteraceae; Zostera.
OX NCBI_TaxID=29655 {ECO:0000313|EMBL:KMZ75928.1, ECO:0000313|Proteomes:UP000036987};
RN [1] {ECO:0000313|Proteomes:UP000036987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Finnish {ECO:0000313|Proteomes:UP000036987};
RX PubMed=26814964; DOI=10.1038/nature16548;
RA Olsen J.L., Rouze P., Verhelst B., Lin Y.-C., Bayer T., Collen J.,
RA Dattolo E., De Paoli E., Dittami S., Maumus F., Michel G., Kersting A.,
RA Lauritano C., Lohaus R., Toepel M., Tonon T., Vanneste K., Amirebrahimi M.,
RA Brakel J., Bostroem C., Chovatia M., Grimwood J., Jenkins J.W.,
RA Jueterbock A., Mraz A., Stam W.T., Tice H., Bornberg-Bauer E., Green P.J.,
RA Pearson G.A., Procaccini G., Duarte C.M., Schmutz J., Reusch T.B.H.,
RA Van de Peer Y.;
RT "The genome of the seagrass Zostera marina reveals angiosperm adaptation to
RT the sea.";
RL Nature 530:331-335(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=glutathione + RX = a halide anion + an S-substituted
CC glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925,
CC ChEBI:CHEBI:90779; EC=2.5.1.18;
CC Evidence={ECO:0000256|ARBA:ARBA00000710};
CC -!- SIMILARITY: Belongs to the GST superfamily. Phi family.
CC {ECO:0000256|ARBA:ARBA00010128}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMZ75928.1}.
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DR EMBL; LFYR01000112; KMZ75928.1; -; Genomic_DNA.
DR STRING; 29655.A0A0K9Q3R3; -.
DR OrthoDB; 1404190at2759; -.
DR Proteomes; UP000036987; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0043295; F:glutathione binding; IBA:GO_Central.
DR GO; GO:0004364; F:glutathione transferase activity; IBA:GO_Central.
DR GO; GO:0006749; P:glutathione metabolic process; IBA:GO_Central.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR CDD; cd03187; GST_C_Phi; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR040079; Glutathione_S-Trfase.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR004046; GST_C.
DR InterPro; IPR034347; GST_Phi_C.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43900; GLUTATHIONE S-TRANSFERASE RHO; 1.
DR PANTHER; PTHR43900:SF3; GLUTATHIONE TRANSFERASE; 1.
DR Pfam; PF00043; GST_C; 1.
DR SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR SFLD; SFLDG00358; Main_(cytGST); 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50405; GST_CTER; 1.
DR PROSITE; PS50404; GST_NTER; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000036987};
KW Transferase {ECO:0000313|EMBL:KMZ75928.1}.
FT DOMAIN 6..91
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT DOMAIN 99..226
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
FT REGION 278..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 490..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 718..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 858..892
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 965..994
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1024..1059
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1092..1121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1172..1216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1229..1263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1297..1467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1488..1861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1888..1919
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2091..2110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2148..2216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2411..2498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2534..2555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2631..2700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2727..2934
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..299
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 490..522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..576
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..643
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..658
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..682
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 718..755
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 756..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 798..820
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 858..891
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 965..983
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1107..1121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1172..1187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1194..1216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1303..1317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1318..1332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1334..1361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1362..1377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1379..1404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1405..1419
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1438..1457
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1488..1512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1519..1543
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1547..1565
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1566..1582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1590..1615
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1693..1714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1715..1732
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1735..1755
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1770..1802
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1812..1836
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2091..2109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2148..2177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2452..2466
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2467..2498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2540..2555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2631..2670
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2672..2697
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2727..2866
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2886..2913
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2914..2934
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2934 AA; 332031 MW; 9E3BEF18A2A74D1D CRC64;
MTDAVVKVYF GNLMMLPDVS RVITCLHEKN VKFDLINMSK ERKHTVPFDF LKLQENPSSR
VLGPVFDDGS KMLFESREIC RYLPENYAEQ GNKYLLGTNT LDRASIEQWI RSEKHSFDPP
SWNLMFHLAF ASLMDLEPKR ALIQESEKKL SQLLDVYNQR LADSKFLAGN HFTLADLVHL
PNTHYLANSK EWSYLFTSRK NVKKWWKKIS QRESWLQTIQ RIDQVVNEGR PSLVSSSSKG
IVSRKSQVYP AKITELSIDD HISSPSKLKD HQQYFSLHKP ETFQSPKKHK KKKKSTKSSK
VASPRMSHQT EAFRQSNVHF DQLEENPLKR SISPISFGHD PLPIPQSKII SPSNKPTIEI
EPSNPHDLPE IPFLEIESPK TEPIVHTQPI DIPTFNPQKS PPPTHKKKIQ PKPSGKIATS
IPHVHMPNWE TYEFYEASMH PESNLPEHLH KTKKNIEDEV SQSHIFYSQK VPPETKYYKL
EPTTSSIQHI QKITATPVEN TTTEPKLRTK ENSNQNPTFP VPLEPGTSYY KKESPKPSQE
NIENSTSAIH GFDQPQPTKQ SQEPPSKNST KETSSKLALF MPTQSEYVPY TKQPTVPHPG
KTGIPEGNTL HTMNLKQRSS IPPETQVSVS KPSIDLSSHV QETNTHDQLD EHLKKEFAHT
PINPSISVSQ PNDFQLSQTK DDLPYPKSED SQFIHLLDQM DEFNPSRKIH PSIVPQKEDL
EPIGPKHETN HQKPPVHVFR RDSGEKKEKF GHKKAQDNQF SQNYMEKKEN RNLSQSTYLS
KSAQLESSKP LPAPVELETN TPSKQLNALQ SPKAKNDLTY PNAENTEITD NLMKKKNEFI
SEEPGMISYL NLPKEENSKI HKHKDRTSEC KPLDPFLSQD SKEKRADLSP PEHFLLKNTL
SEPLNQSLNS PEPKSKAYLQ SSEIKNDIQD IDSEDIQIIK YINKNNVDDL YPLGTTIPSV
ISEEDSNFSE PTVEISHQKS IDQPPSQESE KKRENLILQD LTASHKLTQL EYLQIEDELL
ESQAHELDAR RPHEKSYKSD PHELEPSQHS HGNLEPFKLD KPKFIHQEDN RLYKPSSKIK
LPAQDKSYLV EESKENNFFD KPKSPETASL EPTSQSLSVP EQKSLETLAE TTHFELYNHE
RKTAQVFGQE KNATDFVDPT HKKVISTKLP ILLNPQPFSN PSMQNGEKIT PVIPEETTPT
TKPKFPTQET NEFPISIKTS PQHVFQKKIT PSQQPTVVDP HKYLSSDTPY HKIESPQPSQ
GNIEQFIGSI NESDDHGYDQ PQLIRNAQGI EFQKPELKNI EPFEQSLDSQ THKLEPLQNG
QKESEKEFTQ NLFRPFDPDS QSKDLRSSQT KIGIQYHESK DTQSIEYLDK MTEFDPKLSE
TETPMSQDTE ENGTNLNDKN PQDKPVSDGS QEKRERKTLP VASQLVLFKK VPKSVESETQ
ESLHYPDIQP QPQNDLSDQD SKDTEFSYYL EKKKNDFILE NTNVSESKAK TIHQKPLDPS
MNTSSQMSHP DTLKISEPPI DQKFQNSKSQ EPVKETQVMP GETNTLRDLP KDVKSAERQM
EEKETTYFLD SNLQSTQKEV ILPSKLPTFM GKQPESSQLV QSFTEKKSST PPKQIIDPSK
LPKDSISVEQ DVPRPLKNTS EKLPLPTQAK SPRSPKPLDE KKEDPNTSEL PLLPTPENEA
IHSFKPSQES LDKKRVSTSQ SLIIPSTGAD IDTSDIKSEP SKLTKFDKRE ELNNNQPPLL
PTQDVRANQS FKLSNDSDMQ KHKGQEIVKS SVEETFSSTM KPSPIPTSQE EPSKQTQMKT
PIQEMLGEAA SEHNQAETSL NQERLQPLQR VKISPIDTQS GFPKPVEEPL EKKEASTPQS
IIIPSTEAGI YPIDVISEPF KLKKFYKKKE SNTRQPPLLP DELDDGTNQS IKPSTESYMQ
KQQDERIVKS SVDEIISTAM KSSHLPTSQT ELSRQAQTPV EGILGESSYQ TEAPLIQEGF
QLQQKKSLPI DNRYLKPAQE PLEKKETSTL DSIIIPTTQP EINLMNINSK PSKAITGTNE
NGEKLEKTRL PFLLTPNDGA NQPHFKPASD SYKQMQQVPK DTERLDEYTI SSSTMKPSHL
PTSQSEPFKQ AEKPVEEIHG ESVYRQDQTE IPLTKKLFQP LQKVQSSLID TSPGFPTNAE
ESMEKNETST PQSILIRKTQ PEIYPMNIKS GSSKDIKGTD EKGEGSKTGK PPTLAIQEDR
ANQPLINDFS QMSHPETLKI SEPLINQDFQ NPRLQEPLKE TKVMSEATNA LSDLPQGVKS
VDRKMEEKEA TNFLDSTLQY TQKEVNSPSE LSTFLSNQQE NPQPVQSFIE KKTSALQKQT
IKPSKLDKDS IPVEQDVSKM PKNTLETLPL SKKTQMKTPI QEILGEAASQ QNQAETPLNQ
ERFQPLQRVQ ISPIATQSGI PKPEEEPLEK KEVSTPQSII VPSTEAGIDP TDIKSEPSKL
KNFYKKEESN TSQPSFLPEL DDEPNQFSKP STEPYMQKQQ VQRILKSSAD EIISSTMKLS
HSLTSKAELI EEILDESSSQ KDQAKPSLIQ EGSQPFQQVQ TLDTMKPTPI STFQSDPPKN
VQTTIEKVFG QSPSEPTKME AHFRQEDPQP FEQKLNSMAY TSKPFIYTKN FNEDKQISTP
INNTQPEERS NPPQGPKENI KSSNIPKPYL STPKDENHKL SEKLLETPKK EPNVSDYTES
SLDETINSLI VNSPVLPFPN LESPKQIQTF AEKELSQNKP PTNTQGVPQS IEEVTSLTET
QKKSSVHPQN LTGTSSFTKS SLPKDTSSST KPFLPKDTSS STKPTLPTPQ NEVNQPFKLP
IDSSSRTPSL KSNPSNNSRD TKPAQTSTEQ IVRQNIFKTS EVALLSQENY PRPLDELERS
ETKSPEETPL AQNYSKPTPT KTQTDDKPSS INSPSSPQLP PPKKSQSPEP PTGP
//
