ID A0A0K9XK43_9ACTN Unreviewed; 1274 AA.
AC A0A0K9XK43;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Amino acid adenylation protein {ECO:0000313|EMBL:KNB53739.1};
GN ORFNames=AC230_03805 {ECO:0000313|EMBL:KNB53739.1};
OS Streptomyces caatingaensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1678637 {ECO:0000313|EMBL:KNB53739.1, ECO:0000313|Proteomes:UP000037288};
RN [1] {ECO:0000313|Proteomes:UP000037288}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CMAA 1322 {ECO:0000313|Proteomes:UP000037288};
RA Santos S.N., Gacesa R., Taketani R.G., Long P.F., Melo I.S.;
RT "Draft genome sequence of Streptomyces sp. CMAA 1322, a bacterium isolated
RT from Caatinga biome, from dry forest semiarid of Brazil.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNB53739.1}.
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DR EMBL; LFXA01000002; KNB53739.1; -; Genomic_DNA.
DR RefSeq; WP_049714466.1; NZ_LFXA01000002.1.
DR AlphaFoldDB; A0A0K9XK43; -.
DR STRING; 1678637.AC230_03805; -.
DR PATRIC; fig|1678637.3.peg.836; -.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000037288; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020459; AMP-binding.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR000415; Nitroreductase-like.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR020802; PKS_thioesterase.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR PRINTS; PR00154; AMPBINDING.
DR SMART; SM00823; PKS_PP; 1.
DR SMART; SM00824; PKS_TE; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000037288}.
FT DOMAIN 928..1003
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1274 AA; 139516 MW; BCC9DA5103B52B60 CRC64;
MRAATLDLAT LPGALRARAG AQADSTAVVA GDDSLTYQEL TERSTRTAAL LHRLGVRRDD
RVGIFADPSL DLVVGVWGTL AAGGAYLPLS PEYPEERLRY IIEDARARVI LCRPQLTGRL
RELAPAGTRV VTLDEAAGEE PVLPDEAGPR PDSLAYVIYT SGSTGRPKGV MVEHRSVVSQ
MRWLASAGHL DDDSVVLQKT PMSFDAAQWE ILSPAWGARL VMGAPGVYRD PEGLVDTIVR
HGVTTLQGVP TLLQALVDTE RLGGCTTLTR VFSGGEALTR SLAGELLAEL PGVRLVNLYG
PTECTINSSA HTVSPATLHD EPAVIPIGTP VDGTGYHILD EERRPVGPGE IGELYISGVQ
LARGYLHRPD LTEERFLHLP PAPGAEPVRL YRTGDLAHRD ADGTVHFAGR TDSQVKLRGY
RVELDEIART IEDHAWVKRA AVVVKDDPRT GFQNLIAAVE LNPKEAALMD QGNHGAHHQS
KASRLQVKAQ LANPGLREDH ELAGRPHVDL PGRTADARMR REVFARKTYR FYEGGPVSRA
DVVKLLDQAA DGPAAVRPRR PGDLTLGELG TILRWFGQFH SEERLLPKYA YASPGALYAT
QLYLEAEGVA GLRAGLYYHN PLTHRLTLVR ELDEGGPERL KAHFIGKRRA IEPVYRNNLL
EVLEFETGHM VGLFERVLPA YGLAIHPDGR RPELKPLFDV ADEDHYLGCF DIRRGDGPRP
EDPVDLYVQA HPGKVADLPA GQYRYVCGGL ERVSAELVQK KHVIAINQAV YERASIGISA
VSRAAEPWLE YIVLGRKLHH LQANGLGFGF MSSGYSSKSG NPLPAARRLD AILTERSLPT
GASYFFVGGR VDDGQRASEG MGEDIVHMKG PTEMIRDDLI AYLPDYMLPN KVVVLDALPQ
TANGKIDVKA LAAMEQLTQG LEQREFVPPR TATEQALAGL WGAALKYEPV SKTDNFFESG
GNSLLAVTLV NRVNRHFGTA LPVQVLFETP TVEQLARRID GGGAEESSRL VRLHAKGGEA
PVFCWPGLGG YPMNLQLLGS RVDLGRPFYG IQAHGLNAGE EPYPTIREMA AADLEEIRRI
QPEGPYTLWG YSFGARVAFE AAWQLEQAGE RVENLFLICP GNPTVRTRDG EQHDRTATYC
NPAYLTVLFS VFAGTISGPD VDRCLECVKD EDDFTEFVHD LIPALDTELI RRIVRMVAET
YEFDYSFREL AERSLRTPVT LFKAVGDDYS FIEGSSGYSA LPPAVIDLAG DHYGVLKEHG
VGELVSAIRT RLGH
//
