ID A0A0L0C0B0_LUCCU Unreviewed; 1130 AA.
AC A0A0L0C0B0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 13-SEP-2023, entry version 30.
DE RecName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=FF38_10380 {ECO:0000313|EMBL:KNC25757.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC25757.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC25757.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC25757.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC25757.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC25757.1}.
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DR EMBL; JRES01001072; KNC25757.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0C0B0; -.
DR STRING; 7375.A0A0L0C0B0; -.
DR EnsemblMetazoa; KNC25757; KNC25757; FF38_10380.
DR OMA; EGMAMWK; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd07605; I-BAR_IMD; 1.
DR CDD; cd11779; SH3_Irsp53_BAIAP2L; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR027681; IRSp53/IRTKS/Pinkbar.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14206; BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR14206:SF7; INSULIN RECEPTOR SUBSTRATE 53 KDA, ISOFORM A; 1.
DR Pfam; PF08397; IMD; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51338; IMD; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..242
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 324..385
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 248..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 687..744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 807..884
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 971..1130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..410
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..453
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..485
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..561
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..709
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..744
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 815..884
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 971..996
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 997..1026
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1027..1090
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1109..1130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1130 AA; 129783 MW; F05469DA5B22499A CRC64;
MESEEITKLV DGVYKNILEK FNPGARQLIS AGKGYLKSLH GAATSARLFN EALAKIAMNA
QHSGTGDIGA ALLNVVSVYK EIQEQQMNIL KAFYVDLLVP LETNLEKDTK VVQHEQKKFM
QQHKVRMESY HKAVTTMKKQ RKKKASPENT EKELRTLQIL EDQKKKLDAF CEQSYKNAMT
QERRRYGFVL ERQCSIAKHW MAYHTTGKSV IDNHLENWQE IAASREILPT TVYDGNSMLV
GNKRLERLKD SDDSHASNQS NQLKKSRSVD APFGDMRTLH ETNIPPFTQN SLPRAKSDFN
LNSSGSNSTT TVIANDHSDH GHWDQRTVVK ALYAYMPSGE NQLPFEEGDR IALVGGKAKG
WQFGENLRTQ MFGWFPVAYT NADLIADNKM NKMDRERPER SNDRYENMHY ERQSGGGMRN
SYHENYNDMD NQQEMESDST YRRDRHEEAS PTRMFGDTYR NQKKYRPSSS GNPRPGPPPT
LPAPVPSAQS SARMLNSSQS FCAPNGSQSA IERRNKKLLN GNQITHNRLF LTRQQSSMNQ
LKPAAAAKTS LHSSNDSGFA NEPPPQPEVD YSDEEQTSRV PIRRRADTNT HISTNREIAS
WTLNRNFRSS VDSQIDDKSL KTLNRNSAKM RYDLIASDDE ILQASSGGIK RTKSFWKFGG
GRHDDILAGM SLWQHRDLVA APNMEELRDE GYRTTSSKME SEREMEGNET LNKSNSNNST
SSQEKHDKHL VEQGRGRKDS VTSLEMYDED ENIYGLTPIV RESMPMRSNN NNFTPKSRMK
IMKTIEIDIE NPTESERLST IKRNQKEYQK EYRESTLNRN SIMENKKQNS LGNRGQNSNH
KKSYDIPKNS HNMGQNKNMN GAAPNRTNKQ TEMFPSTESE AGESELDNGT LKMSDVNNFF
DNNGNSGGII MKTVKRKDIL KQYYTSEDDS DDPEIKSTSS DPYDCIVIND HLVRRDEKQR
RALQMQEHQM EFQTFRSSTS NTNLQQNGNN MNMNTNTKKK SERREPSERR GGAEQDQERS
RSSKSYEHHQ QQQQQQQEQM RYEDSTLTRQ SNSSLNTPTA TILPRTRLMK SSNMSSMTLE
RNTNSQSQQK SLSDRDKHYG KTYGPWYDFW DQQDQQQQMQ QQQQNKNKMK
//
