ID A0A0L0CQC2_LUCCU Unreviewed; 767 AA.
AC A0A0L0CQC2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
GN ORFNames=FF38_09357 {ECO:0000313|EMBL:KNC34575.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC34575.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC34575.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC34575.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC34575.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC34575.1}.
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DR EMBL; JRES01000049; KNC34575.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0CQC2; -.
DR STRING; 7375.A0A0L0CQC2; -.
DR EnsemblMetazoa; KNC34575; KNC34575; FF38_09357.
DR EnsemblMetazoa; XM_046954698.1; XP_046810654.1; LOC111686179.
DR OMA; YGQQGSW; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd22397; KH-I_FUBP_rpt2; 1.
DR CDD; cd22398; KH-I_FUBP_rpt3; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 4.
DR InterPro; IPR015096; FUBP_C.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR PANTHER; PTHR10288:SF171; P-ELEMENT SOMATIC INHIBITOR, ISOFORM C; 1.
DR Pfam; PF09005; DUF1897; 3.
DR Pfam; PF00013; KH_1; 4.
DR SMART; SM00322; KH; 4.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 4.
DR PROSITE; PS50084; KH_TYPE_1; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 125..193
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 216..287
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 335..406
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 444..515
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 20..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 289..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 617..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 767 AA; 79782 MW; 24EF239CF79F368A CRC64;
MGDFGGSTAA QSNINQSQAF AAALQRAKQI AAKIQPNPQQ GGNNSGGGGG GGGGAGFKRS
LDDSDSGPEN KRFTSPDAND YGHNSNSNMS GGGGSSSGGG GPANMTQAIA QAAAVAARLA
ATAGNTCEEQ VRIPDCLMSA FYGRGNNETI SHIQGDSGCK VQMSQTEGER ILTLRGSRES
VTKGREVMQQ LANRNGGGNV EVVLTINMPP PGPTGYPPYQ EIMIPGTKVG LVIGKGGDTI
KQLQEKTGAK MVIIQDGPNQ EVIKPLRISG DPHKIENAKQ LVLELIAQKD AQQQQQQQQQ
NNRPNMGGNG GGMGSNNGPN NGGGNYNNFG GGNNGGEQCE VFVPKLAVGV VIGKGGDMIR
KIQQECGCKL QFIQGKNDEP GDRRCLIQGS RQQVDDAKRM IDGLIDNVMQ RNRNGNGGGG
GNGGDNGNSN YGYGYGVNHA QQPAREEITF MVPASKCGIV IGRGGETIKL INQQSGAYCE
MDRNAVNPPS EKLFKCKGTS EQVEAARQMI AEKINMELPI INRKSINGGP PNQQGGGGGA
GGYNPNDPNA AAAAYQQQWA AGYGQAGGWG DQAQQQQAAG MGQAAQAAAS QSADYSTQWI
EYYKSMGMHR EAEMIEQQLK AKQASAAPQP QTQAQPAAQQ AQSAGQQSQD YSAQWAEYYR
SIGKIEEAEA IEKQMKASQS SASTAASSSS SSASAAGASA GGGGGCSAGT YTPSGGISSG
GISSSVAVAG QQTNDYSAQW AEYYRSIGKI EEAEALEKQL KVRCVFF
//
