ID A0A0L0DPG0_THETB Unreviewed; 613 AA.
AC A0A0L0DPG0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273};
DE EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};
GN ORFNames=AMSG_09550 {ECO:0000313|EMBL:KNC53911.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC53911.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC53911.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC53911.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|RuleBase:RU004273};
CC -!- SIMILARITY: Belongs to the PPP phosphatase family.
CC {ECO:0000256|RuleBase:RU004273}.
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DR EMBL; GL349484; KNC53911.1; -; Genomic_DNA.
DR RefSeq; XP_013754117.1; XM_013898663.1.
DR AlphaFoldDB; A0A0L0DPG0; -.
DR STRING; 461836.A0A0L0DPG0; -.
DR EnsemblProtists; KNC53911; KNC53911; AMSG_09550.
DR GeneID; 25567988; -.
DR eggNOG; KOG0375; Eukaryota.
DR OrthoDB; 1488111at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0033192; F:calmodulin-dependent protein phosphatase activity; IEA:InterPro.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0097720; P:calcineurin-mediated signaling; IEA:InterPro.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR043360; PP2B.
DR InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR PANTHER; PTHR45673; SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED; 1.
DR PANTHER; PTHR45673:SF1; SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED; 1.
DR Pfam; PF00149; Metallophos; 1.
DR PRINTS; PR00114; STPHPHTASE.
DR SMART; SM00156; PP2Ac; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR PROSITE; PS00125; SER_THR_PHOSPHATASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU004273};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408}.
FT DOMAIN 174..179
FT /note="Serine/threonine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS00125"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 420..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 67493 MW; 0732D322C5584D0D CRC64;
MSSAGASSRR SRERSTSRSR SASPKLAAIV DRYDIPEDTA VRMCTVVPAP RRPAMSADEL
FSGPGGDVNT DLLLQHLRTE GRLSLEAASQ LLETAREVLS REPNCVPLEA PMHIVGDIHG
QFYDLLHMFD SLGLPPKRKY LFLGDYVDRG IYSTEVAILL LGLKIRYPEH VTLIRGNHES
RAMAAYHSMK TETLYKYSET TYNEFMEAFD ALPVAATVAG PAGTFLCVHG GLSPAVNTIE
AINALARFGE VPASGPLCDL MWSDPVPDAT ATGLSGSQLR QWKEITFEFN EQRGCSYRYG
RRAVRDFLTA NGLVGIIRAH EVQENGYNEH RFREEAEDDP LSPFPLVTTV FSAPNYCEMY
DNSAAVALYD GTTLEFVSYE CVEHPFGLPD YMDSLNWSLP YVMEKVTQFF AVSLKLIEGD
SDSDSDDDEP MQTDAGPASP VSRKASAKAL RDAARAAAAR KRANQKAAAE APEPATAPDT
AASEPPASSA AASAAGTPGS SADDASAPEG DDAAAFRSRT SRVRTRKRPA MRQRSSSNIC
NETIRTRRAS MNTLLRRAEK LRERNMRLLV AANDDDDDDD DDAADDTLSR FERALRKDSK
REYLRPLQRH YTM
//
