ID A0A0L0G4F9_9EUKA Unreviewed; 456 AA.
AC A0A0L0G4F9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=1-phosphatidylinositol 4-kinase {ECO:0000256|ARBA:ARBA00012169};
DE EC=2.7.1.67 {ECO:0000256|ARBA:ARBA00012169};
GN ORFNames=SARC_04632 {ECO:0000313|EMBL:KNC83093.1};
OS Sphaeroforma arctica JP610.
OC Eukaryota; Ichthyosporea; Ichthyophonida; Sphaeroforma.
OX NCBI_TaxID=667725 {ECO:0000313|EMBL:KNC83093.1, ECO:0000313|Proteomes:UP000054560};
RN [1] {ECO:0000313|EMBL:KNC83093.1, ECO:0000313|Proteomes:UP000054560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP610 {ECO:0000313|EMBL:KNC83093.1,
RC ECO:0000313|Proteomes:UP000054560};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Young S.K., Zeng Q., Gargeya S., Alvarado L., Berlin A.,
RA Chapman S.B., Chen Z., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Howarth C., Mehta T., Neiman D.,
RA Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., White J., Yandava C., Burger G., Gray M.W., Holland P.W.H.,
RA King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Sphaeroforma arctica JP610.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ241864; KNC83093.1; -; Genomic_DNA.
DR EMBL; KQ241864; KNC83094.1; -; Genomic_DNA.
DR RefSeq; XP_014156995.1; XM_014301520.1.
DR RefSeq; XP_014156996.1; XM_014301521.1.
DR AlphaFoldDB; A0A0L0G4F9; -.
DR STRING; 667725.A0A0L0G4F9; -.
DR EnsemblProtists; KNC83093; KNC83093; SARC_04632.
DR EnsemblProtists; KNC83094; KNC83094; SARC_04632.
DR GeneID; 25905136; -.
DR eggNOG; KOG2381; Eukaryota.
DR OrthoDB; 1332545at2759; -.
DR Proteomes; UP000054560; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:UniProtKB-EC.
DR InterPro; IPR039756; Lsb6/PI4K2.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR PANTHER; PTHR12865:SF1; PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2; 1.
DR PANTHER; PTHR12865; PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000054560}.
FT DOMAIN 2..437
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT REGION 207..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 456 AA; 51292 MW; 4659CF7CC9B805C9 CRC64;
MGIHPTLIRQ GSSGSYFVRN PEAKITGVFK PKDEEPYGHL NPKWTKWLHK TICPCIFGRS
CLVPNQGYLS EAGASLVDEK LGLRIVPTTK VVKLSSPVFN YPRTTRLYRL LKSDQSLPYK
KGSLQLFVTG YEDAKKVFGR VNAPDYRDHE VKREFDMLFE RMVVLDYITR NTDRNDDNWL
IKTLNDSGSN APESDLGVDL CTGISPVTTA PHTNTRTQAS PKQMPNNANS SGSNLPSSTN
TPRQLGRSSL SGSLNVNGPV AYHRRSPSAH ETSISAPEPL GSSNLGQGIG GQSLYTGSSA
SNKGSGLELH DIQRSTELPE CHRVKLAAID NGLSFPFKHP DSWRTYPYHW IWLPQAKKRF
SDEICNYLLP LLTDEVYVEE LIEEMYQVFK QDSGFSKSHF KRQAAVMRGQ ILNLTKAMNE
RSTPIQLVKM TSCVIKKKGQ SKFQQFRSRL PWFSNW
//
