ID A0A0L0JTS7_9ACTN Unreviewed; 329 AA.
AC A0A0L0JTS7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KND28855.1};
DE SubName: Full=Lactose operon repressor {ECO:0000313|EMBL:GAQ53483.1};
GN Name=lacI_3 {ECO:0000313|EMBL:GAQ53483.1};
GN Synonyms=lacI_4 {ECO:0000313|EMBL:GAV45863.1};
GN ORFNames=a10_03288 {ECO:0000313|EMBL:GAQ53483.1}, IQ63_32540
GN {ECO:0000313|EMBL:KND28855.1}, Saa2_08862
GN {ECO:0000313|EMBL:GAV45863.1};
OS Streptomyces acidiscabies.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=42234 {ECO:0000313|EMBL:KND28855.1, ECO:0000313|Proteomes:UP000037151};
RN [1] {ECO:0000313|EMBL:KND28855.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NCPPB 4445 {ECO:0000313|EMBL:KND28855.1};
RA Chen X.-L., Norrbom A., Zhu C.-D.;
RT "A systematic study of Ichneumonosoma Meijere, Pelmatops Enderlein,
RT Pseudopelmatops Shiraki and Soita Walker (Diptera: Tephritidae).";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000037151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 4445 {ECO:0000313|Proteomes:UP000037151};
RA Harrison J., Sapp M., Thwaites R., Studholme D.J.;
RT "Genome sequencing of plant-pathogenic Streptomyces species.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000058287, ECO:0000313|Proteomes:UP000186713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=a10 {ECO:0000313|Proteomes:UP000058287}, a2
RC {ECO:0000313|Proteomes:UP000186713}, and A2
RC {ECO:0000313|EMBL:GAV45863.1};
RG Cross-ministerial Strategic Innovation Promotion Program (SIP) consortium;
RA Tomihama T., Ikenaga M., Sakai M., Okubo T., Ikeda S.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:GAQ53483.1, ECO:0000313|Proteomes:UP000058287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A10 {ECO:0000313|EMBL:GAQ53483.1}, and a10
RC {ECO:0000313|Proteomes:UP000058287};
RA Tomihama T., Nishi Y., Sakai M., Ikenaga M., Okubo T., Ikeda S.;
RT "Draft Genome Sequences of Streptomyces scabiei S58, Streptomyces
RT turgidiscabies T45, and Streptomyces acidiscabies a10, the Pathogens of
RT Potato Common Scab, Isolated in Japan.";
RL Genome Announc. 4:e00062-16(2016).
RN [5] {ECO:0000313|Proteomes:UP000058287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=a10 {ECO:0000313|Proteomes:UP000058287}, a2
RC {ECO:0000313|Proteomes:UP000186713}, and A2
RC {ECO:0000313|EMBL:GAV45863.1};
RA Tomihama T., Ikenaga M., Sakai M., Okubo T., Ikeda S.;
RT "Draft genome of pathogenic Streptomyces sp. in Japan.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KND28855.1}.
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DR EMBL; BCMK01000022; GAQ53483.1; -; Genomic_DNA.
DR EMBL; BCML01000146; GAV45863.1; -; Genomic_DNA.
DR EMBL; JPPY01000183; KND28855.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0JTS7; -.
DR STRING; 42234.IQ63_32540; -.
DR PATRIC; fig|42234.21.peg.6697; -.
DR eggNOG; COG1609; Bacteria.
DR Proteomes; UP000037151; Unassembled WGS sequence.
DR Proteomes; UP000058287; Unassembled WGS sequence.
DR Proteomes; UP000186713; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01574; PBP1_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037151};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..53
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 329 AA; 35321 MW; 1DCB1B3699FB0FB9 CRC64;
MADVARVAGV SSQTVSRVSN GYAGVTEETR RQVLDAMREL GYRPNSAARA LKRGEFRTLG
VITFSLSSTG NVRTLEAIAN SAAAEGYAVT LLPVAVPTQD EVRGAFTRLE ELAVDAVIVI
MEVHLLDAAT INLPPYVQVV VADSDAGERY TVVDTDQAGG TRTAVQHLLG LGHRTVWHLS
GPEDSFAAQR RTDAWRETLV QAGRPVPPPV SGDWSAESGY RAGLDLAARE DCTAVFAAND
QMALGLLRAL HESGRRVPED VSVIGFDDIP EASSFLPPLT TLHQDFAEVG RLCVRAVLRK
MRHDGPTHGT TLVPTRLVVR ESTAPPPGR
//
