ID A0A0L0VDS4_9BASI Unreviewed; 1134 AA.
AC A0A0L0VDS4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Upf1 domain-containing protein {ECO:0000259|PROSITE:PS51997};
GN ORFNames=PSTG_09261 {ECO:0000313|EMBL:KNE97428.1};
OS Puccinia striiformis f. sp. tritici PST-78.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=1165861 {ECO:0000313|EMBL:KNE97428.1, ECO:0000313|Proteomes:UP000054564};
RN [1] {ECO:0000313|Proteomes:UP000054564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race PST-78 {ECO:0000313|Proteomes:UP000054564};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Hulbert S., Chen X., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Puccinia striiformis f. sp. tritici PST-78.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family.
CC {ECO:0000256|ARBA:ARBA00007913}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01341}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNE97428.1}.
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DR EMBL; AJIL01000068; KNE97428.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0VDS4; -.
DR STRING; 1165861.A0A0L0VDS4; -.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000054564; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR CDD; cd21407; 1B_UPF1-like; 1.
DR CDD; cd18039; DEXXQc_UPF1; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR CDD; cd21400; ZBD_UPF1-like; 1.
DR Gene3D; 2.40.30.230; -; 1.
DR Gene3D; 6.10.140.1240; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR040812; UPF1_1B_dom.
DR InterPro; IPR018999; UPF1_CH/ZBD.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF364; REGULATOR OF NONSENSE TRANSCRIPTS 1; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF18141; UPF1_1B_dom; 1.
DR Pfam; PF09416; UPF1_Zn_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51997; UPF1_CH_RICH; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU01341}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054564};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01341};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU01341}.
FT DOMAIN 118..280
FT /note="Upf1"
FT /evidence="ECO:0000259|PROSITE:PS51997"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 64..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..220
FT /note="C4"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01341"
FT REGION 934..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1083..1110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1134 AA; 125382 MW; A058D4D97A85357A CRC64;
MENFSHLQGA SEYSYNPAND DDDSLSLLSA DTRGPGNPAN RHHVEGRDSL STIDDINFDE
LSLLDVNPEP NNRNRHQANN SANYDHHQAR SDSTVDQPSQ FNQNETEADF EDVLDDLNRE
LPGHACAYCG IHSPSSVVKC LICSKWFCNS RGGPGAHSTG SHIVNHLVRA KHKEVTLHED
GPLGETTPEC YNCGSKNVFT LGFIPAKSDT VVVLLCRQPC ASTPSSKSDL VWDTSQWSPL
IEDRQFLSWL VKVPDEQEVV RSKPVGFREI TRLEEMWKEN ATATLDDLER DGALGEGEPQ
PILLRYEDAY QYQNIFGPLV KIESDYDRKL KESLTQNDVT VRWDMGLNQK RIAYFYLPKL
ESGEVRLAVG DELRLRYSGE LQQAWEGPGH VIKVPNNQSD EVALELRRNE GVPHELTVNF
SVDFVWKSTS FDRMQMAMKT FAVDDQSVSG YIYRKLLGAE ATVPQVLRTQ MPKRVSAPNL
PELNHSQVSA VKSVLQKPLS LVQGPPGTGK TVTSASVVYH LSKMNPGQVL VCAPSNVAVD
QLTEKIHMTG LKVVRVQAKS REAIDSSVQY LTLHQQVANN DTHPDLQKLI QLKAEQGELS
STDERRFKSL TRLCEREILT TADVILCTCV GAGDPRLAKM KFRTVLIDEA TQATEPECMI
PLTLGVKQVV MVGDHQQLGP TIMNKKAARA GLTQSMFERL VLLGNRPIRL QVQYRMHPCL
SEFPSNMFYE GSLQNGVTAP ERIKKNVDFP WPQPATPMCF HSNLGQEEIS SSGTSFLNRT
EASNVEKVVT RFFKAGVLPS QIGIVTPYEG QRSYIVTYMQ TNGSLKKELY KDIEVASVDA
FQGREKDYII LSCVRSNDHQ GIGFLNDPRR LNVALTRAKY GVVVLGNPKV LSKHALWHFL
LTAYKEKSCL VEGPLNNLQP SLVQLSKPRK PLDRADLPIN RFEPNPRELP NLNYSRNGRA
STPTRFDQSF YKTVDSFSIP SDAQSVRSQA TYASGLPPFS LPISRGMGYP NGTKRVGGGL
GSAGIGSSSY ASSMISQDLM SQDSRSMRGG GGGGDDTSSV ADSFADNTSL AAYSQADRLL
TGRSRNDRTG LDFRGPGATG PAPVGLGGGN KNFRVDDDDA RSLISMQSSS IIDF
//
