ID A0A0L1I592_PLAFA Unreviewed; 1125 AA.
AC A0A0L1I592;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Deoxyribodipyrimidine photolyase {ECO:0000313|EMBL:KNG74333.1};
GN ORFNames=PFMG_00349 {ECO:0000313|EMBL:KNG74333.1};
OS Plasmodium falciparum IGH-CR14.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=580059 {ECO:0000313|EMBL:KNG74333.1, ECO:0000313|Proteomes:UP000054562};
RN [1] {ECO:0000313|Proteomes:UP000054562}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "Annotation of Plasmodium falciparum IGH-CR14.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054562}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Godfrey P., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Wirth D.F., Nusbaum C., Birren B.;
RT "The genome sequence of Plasmodium falciparum IGH-CR14.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG664981; KNG74333.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L1I592; -.
DR EnsemblProtists; KNG74333; KNG74333; PFMG_00349.
DR Proteomes; UP000054562; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.80; -; 1.
DR Gene3D; 1.10.579.10; DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf.
DR InterPro; IPR036155; Crypto/Photolyase_N_sf.
DR InterPro; IPR006050; DNA_photolyase_N.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR10211:SF0; DEOXYRIBODIPYRIMIDINE PHOTO-LYASE; 1.
DR PANTHER; PTHR10211; DEOXYRIBODIPYRIMIDINE PHOTOLYASE; 1.
DR Pfam; PF00875; DNA_photolyase; 1.
DR SUPFAM; SSF48173; Cryptochrome/photolyase FAD-binding domain; 1.
DR SUPFAM; SSF52425; Cryptochrome/photolyase, N-terminal domain; 1.
DR PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Lyase {ECO:0000313|EMBL:KNG74333.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054562}.
FT DOMAIN 642..775
FT /note="Photolyase/cryptochrome alpha/beta"
FT /evidence="ECO:0000259|PROSITE:PS51645"
FT REGION 217..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..546
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 17..79
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 241..262
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..531
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..546
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1125 AA; 130443 MW; 3B4715DB44B698B3 CRC64;
MASDRDNKVD GIVHEALKKK ETNLFQKSEV IKKLNEERKE KIIIQDGQEN NLDEKKKKKT
IIKNNEDILK DNINNLKNNN KTHININKGI TICEKNNNNN KYEIPIIGAS KRMDDISSYD
EKKDIITNVK ENHVDDKKKN IIIINKEDIQ KDNTNSNVIN NHMRYNKLNA NICKYENVFS
EKGNKTDIIS CTFTDSNKKK QVSFFSQVDK NIMQQTKGNI KKKKKNDEQE EEEEEEEKGK
EEEKEKEKEK VEEKVEEKEK EKEKVETYLK EPINKLLYKE QFCTDIYKME ILKKDENHKK
SIEKNNIVVK GKQNINTSSK NNIFIPLQNN VYLPSQNNVY LPSQNNVCPP LQNNVYLPSQ
NNVCPPLQNN VCPPSQNKAC PSSQNNVCPS SQNNVCPSSQ NNVCPSSQNN VCPSSQNNVC
PSSQNNVCPS SQNNVCPPSQ NNVPPKTHVP SENNKVTKIV KLINEKQQNK GNYRNTKWNN
TINGKKNGTK YITGGSKMLT KDLKKEKSNT PLSKNKLPDI GSPATNNVKE TSLTSDKKKK
KKNPYETSLK NKLNILNKRV RCLTSFENIK DGLANVRNNQ TGGNFKELLL SHDMITKNNN
ITSSSPIMNN NNNIQNSNIM SCDNIHNNNI SPEHNSCVYN KNNVLLLLTR DFRINDNWSL
IYAYEKAKKK KAHLFACTYL NRKEPFPKRH IDIKLKVLKN LEENMKKILN IPFYLLTIYM
IDEFMEFLRI YDIKTIICDF NPLNETRIFI QNLVELSNIK KIKILQVDSH NIVPIWITSK
IEESCARTIK PKIQTHISTF LIEYVQLEMF DQIIKYPEPF SISEVFKKLT VYIPCPVLLN
FVCTEQKAHE ILQNFCSKKL ERYSLKKNDP NSEMINLLTP YINFGIISSQ RCVLEVNKYA
NSYPSINTIS GKELFSEEMI MKKELADNFC YYNKNYDNFN GGKDWAKDSL KKHDSDKREY
LYDFDDFKNA KTHDDLWNCC QLQLINEGII HEFLRMYWCK KILNWSGNSK TALKCAMKLN
DDFSIDAKSP HGYVSIMSSI MGIHDQSWNE RTVFGKIRSM NYNSCKRLFD INVYMSKYPK
GKENALIVQK IPTMTFSSYI KKRKNSNISI EEKKNEKREK KCVAS
//
