ID A0A0L1I5D4_PLAFA Unreviewed; 1193 AA.
AC A0A0L1I5D4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
GN ORFNames=PFMG_00588 {ECO:0000313|EMBL:KNG74405.1};
OS Plasmodium falciparum IGH-CR14.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=580059 {ECO:0000313|EMBL:KNG74405.1, ECO:0000313|Proteomes:UP000054562};
RN [1] {ECO:0000313|Proteomes:UP000054562}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "Annotation of Plasmodium falciparum IGH-CR14.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054562}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Godfrey P., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Wirth D.F., Nusbaum C., Birren B.;
RT "The genome sequence of Plasmodium falciparum IGH-CR14.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR005719}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
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DR EMBL; GG664985; KNG74405.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L1I5D4; -.
DR EnsemblProtists; KNG74405; KNG74405; PFMG_00588.
DR Proteomes; UP000054562; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR CDD; cd03272; ABC_SMC3_euk; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR041741; SMC3_ABC_euk.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 2.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005719};
KW Reference proteome {ECO:0000313|Proteomes:UP000054562}.
FT DOMAIN 505..632
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 227..282
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 332..456
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 667..704
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 740..984
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1193 AA; 141197 MW; F4EDAB6E3B4ADB91 CRC64;
MYIKQIRLKG FRTYKNETTI DFTRGINCIV GFNGSGKSNI LLAIEFILSD VCEYKQIYLH
EGIGNAVRNC YVEIIFDNSE KYFSMFKESE IKIKKVLENM KCEIFVNDKN ISKNQYVELL
ESCGLCINNL YNIIKQGQII KLSNMKDEEI LNYLKSILGA KIFEEKKKDA LSMLKECDSK
KVTIEKEFND MNSKLESLQE EFENFLEYKK LEKEKVHLDY FLNEINYKNI YEETQMLKSK
LQELKNKTQD EDNHLNLSNN NKSEYNEKLN KMKLEIASCQ NHLNKTISED IQNKRNIVHL
QMLIDEKIKE KNIKESQNKN RIKNINQINE FILRVNEKLQ SLKSDIVSKE KQIENKNNEI
NMLLSKNKNK NTDANYSHNV KKIEKMINDI NIELSFLEKE TIKNEKYLKE LEEESKVLNK
SIKENETLSQ KYGSEINELN NKSEKCVEQK RQCQQKISEG TTNLNEIKCQ IIEVNDKYDE
IIKSSNKEIL KIVDLIMAEK SIKRENILGF LIDNINVDKT YVKAVDTILE NHYFTLIVED
MQTAKKIVEF IEKKREEKTS KEFNFKEFYF GKLTIVPLLN IKKFNEFNYP NDKNIVPLIK
CVNYNSKIYE FLKNILFKTI IVKSLESCEN YLEDNYNCVN IDGDYLSKHG FMYGGYNKKK
YGIYTVYNKL KELKEEEKKE KSHIEELNNN IEKIDDELRN IYDTKSSTVA KKNGCASTIN
SINNNIYSNE ENIRLTSEKI NYIQEKKQNL EQHKDQLKMQ ILQLRNNNVN PDESEKVGST
DINSLNDEVK KLKEELNKIR NEYDDFKNKL ELLYQKRNEN DSSIYMEEYE DVDIDEYNND
LADKKDHSDK IEKEKIHYEQ KIREINKEME NVKSSIDKIL INEKKHKKKI LDLCHQMNQI
NEELRILEGK EENIRKKKVL LPQGIQELEE YRTYDKQQLS AKLKSVTMEL KKYSNVNEKA
GDRLNILMND FNELKKRHEE INSSHKNIKD MIQHIGKKKD EALEATYVKI NKYFSEYFSL
LFKNRKASLV LKKMNEKEYK EKLQEMSEKR IKRRIIDEEV YIDKITGISI NITSNDDEKM
TYTIQELSGG ERSIVAICLF LCLNKIDNFS FFFFDEIDAA LDTIHRDNLS LLLKELAHRG
TQFIITTFRK ELLEYSDNMY IVKIVDRESY ISKGTKNEAY EIISIEEKHA LEN
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