ID A0A0L1J9A9_ASPNO Unreviewed; 2212 AA.
AC A0A0L1J9A9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KNG88285.1};
GN ORFNames=ANOM_002507 {ECO:0000313|EMBL:KNG88285.1};
OS Aspergillus nomiae NRRL 13137.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1509407 {ECO:0000313|EMBL:KNG88285.1, ECO:0000313|Proteomes:UP000037505};
RN [1] {ECO:0000313|EMBL:KNG88285.1, ECO:0000313|Proteomes:UP000037505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 13137 {ECO:0000313|EMBL:KNG88285.1,
RC ECO:0000313|Proteomes:UP000037505};
RA Moore M.G., Shannon B.M., Brian M.M.;
RT "The Genome of the Aflatoxigenic Filamentous Fungus Aspergillus nomius.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNG88285.1}.
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DR EMBL; JNOM01000056; KNG88285.1; -; Genomic_DNA.
DR RefSeq; XP_015409208.1; XM_015547764.1.
DR STRING; 1509407.A0A0L1J9A9; -.
DR GeneID; 26804311; -.
DR OrthoDB; 5396558at2759; -.
DR Proteomes; UP000037505; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR GO; GO:0018130; P:heterocycle biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF54; SYNTHASE, PUTATIVE (JCVI)-RELATED; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF08659; KR; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR Pfam; PF21089; PKS_DH_N; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF14765; PS-DH; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00826; PKS_DH; 1.
DR SMART; SM00822; PKS_KR; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000037505};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 23..413
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 2110..2185
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2212 AA; 243235 MW; C5EDF7D63FA646CE CRC64;
MQPKSLQHDE LAALIPDGRP GASPLVAIVG MAMRLPGGVR TTEDFWQFLI NKRDGHCEVP
KMRYGIDGFY NAHDERYTHT RHGYFLPEDP AYFDAPFFSV TEQDASTMDP QQRLLLEVVW
ECLENAGETN WEGKNIGCYV GVFGEDWLGL SHGDPLSIDR SHAISTGSYA LANTVSYKFD
LRGPSMTIQT GCSSSMVGIH EACQSLATGA CSSAIVAGTN LILSPSMTTS MSGNMVLSTS
GVCRTFDAEA DGYGRGEAIN ALYLKPLGDA IKANDAIRAI IRSTAANSDG GTSSIAVPSI
IAQEHLILDA YRRGNINDLS ETAFVECHGT GTRAGDQVET TAVANVFEGQ EIVIGAVKPN
FGHSEGASGI TSVIKAWLGG PSRAYELAGR RRRRVSVNAF GIGGTNAHVI LDSAHDVCAK
DPAQGCIGPE NDVKLLVISA QDAKSLKARI DQVTDYANRH PERSQDLSFT LGVRRKHLAH
RAFAVYDPTS PLSPSDFQSA HPHVSAQLTF VFTGQGAQWP GMGQGLIKAY QCFKMDILEL
ENVLRSIEDP PQWSLMEELS CATASRINEA EFCQPLCTAV QIGVVNLLAA WGIRPASVVG
HSSGEIAAAY AAGAISARSA IILAYYRGKL AQAQKGTGGM ASIGLGSDEV SPYLVDGVVI
ACKNSPQSVT ISGEQGQIDQ MVRNIQNDLP DTFCRKLQLD MAYHSHYMAA VGPIYEKSIS
NHLQLHQQML PMFSSVDVRM ITDPQTLNAA YWRRNLESTV LFSDAISSLF AERHKKHILV
EIGPHCALSA PIQQIIRAYD LKICPAYIPT LFRNDANCQH QLLTSVGSIH RNGAFVDLLA
VNGTGHVLTD ILPYPWQHGT RYWKESRMVR EWRLNEVPPH ELLGSRSTES TSLEPAWRQF
ISLENIPWLS DHIIQGKVVF PAAAYIAMVG EAILQLSPGV VSYTVRNAIF KAPLVIEESE
NVEVITTLRP ARLNDLADSE WFSFTIASYD GTNWIKNCSG QVRAGACGNI SPVSIKPYAR
RVSSSKWYDT LASLGLSYGA QFRGLQDISV DPKGSRAVAK VNNKAGSPAC RYSLHPTMID
QCLQVMSVAG AAGLPRRIAT GAIPASIDQI FIGEGENHME ATVDTVQESG SSLVGDATAI
LGDKVVLKMK RGLCFALGNK NDSISPQTPL VARIQWKPDP DLCKPEDLLP RAATSLGRLD
QMKKLGQVSL LYILETAERI KPLVPQSTHA SKWKSWILYE DAAVRNGEHT LLPESKAWAT
QSSEERQALI KKLSTTQADQ PGEHNIIITC TEVIYENCLE IMANKISTLD LLMEENRLGR
IYQFDQENSD WSIFITYLSH SNPWLRILEI GAGTGSATAE ALRSLCVSGM PMYSKYTFTD
ISPGFMTAAQ GKFRENVNME YKVLDISSDP LKQSFVGQSF DLIIASNVLH ATPVLKQALK
NVKRLLAPHG WLLLHELAPV MPYVDYIMGT LPGWWIGEDD GRINRPYISP EDWDKKLQYA
GFTGTEAIRY DSDTYHLCVD IITRPAPVET ATQPIVLLTD GSPDLWAGKV FSELEKQNFI
VEWGKLEEAP SGHACVVFLL EHRDPFLAKL SEKRYHCLQK YLMGVGQSKL LWVTKTTQFD
CKDPDCGLVL GFARTLRQEM MLDFYTLEID VFDTESAKAV GPIVRKILKP TNRDNQDPNY
EYAYHNNTVF TSQCYWGAAA NILRPSKPDT GKKLSMSIPG LLDTLEWLDS SYGSLGQDDV
EVDIDLLFQF MLWHDEGKIK PIRPTTVFAA CEAIEAFRLM QQGTHIGKIL IRMPDDASQL
SQRPSEVEVL FSSTASYLLV GGLGGLGRAV SRWMVEQGAR YLVYLSRTAG STEEHSEFIQ
ELNAMGCHVE CIQGSVTRTE DVQAAISRCK SPLKGVFQMS MSLNDRPFPH MSYEEWSSSL
SPKVQGTWNL HNSVLQEDLD FFVLFSSAVG ICGHGSQANY AAANTFLDGF TQYRRRLGLP
SSAIALGAVG ETGLVAREAK VMQAMQSIGI WLLNEDEVLE GLKKCIGESN TVDCTESAAR
LSAPLIIGLG NNKSLSNPDI QTMWRRDARF ASYTNLDSIS VKQESGSSVN KIRELIIKAE
LDPLILLQKE TETTITQELN QLIAKSLPGA QDMDDEAKTS LAIDSLMAIE VRNWIRRNLQ
VEISLPEISR ARTAGGLIDM TLTRLKMRYQ VSDTEGTQNA VAETSFDLDT SR
//
