ID A0A0L8H1W9_OCTBM Unreviewed; 249 AA.
AC A0A0L8H1W9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=TGF-beta family profile domain-containing protein {ECO:0000259|PROSITE:PS51362};
GN ORFNames=OCBIM_22024215mg {ECO:0000313|EMBL:KOF83192.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF83192.1};
RN [1] {ECO:0000313|EMBL:KOF83192.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF83192.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF83192.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; KQ419550; KOF83192.1; -; Genomic_DNA.
DR RefSeq; XP_014776149.1; XM_014920663.1.
DR AlphaFoldDB; A0A0L8H1W9; -.
DR STRING; 37653.A0A0L8H1W9; -.
DR EnsemblMetazoa; Ocbimv22024215m; Ocbimv22024215m.p; Ocbimv22024215m.g.
DR EnsemblMetazoa; XM_014920663.1; XP_014776149.1; LOC106873338.
DR GeneID; 106873338; -.
DR KEGG; obi:106873338; -.
DR OrthoDB; 2968469at2759; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13756; TGF_beta_BMPs_GDFs; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 120..249
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 67..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 249 AA; 28836 MW; 4C1C9A1FE1A4C3F6 CRC64;
MFMTKKNLVI NVTAIVKRAT AERSEQLTFK VIHRRRGQHQ SCRLNPNALL IMYSDMFIAD
IKRSQQNNRK SKRLFKTSAE TANSSGEEPE RGLPMQDFPT KTTPNIPTTV KAPSLEEDKR
RRRSLQNTSS SPDQLFNRNF KRHNTTNCSL KPWQIRFSDI RLNWILRPKV YNASYCSGHC
LSLIDSRVSN HAFLRNKYHL STGYNHVHIP YSYCVPSVYS PLPIIYESKL KEVLIGTLQN
MIALDCACW
//
