ID A0A0L8H4F7_OCTBM Unreviewed; 359 AA.
AC A0A0L8H4F7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Protection of telomeres protein 1 {ECO:0000256|ARBA:ARBA00015253};
DE Flags: Fragment;
GN ORFNames=OCBIM_22022639mg {ECO:0000313|EMBL:KOF84092.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF84092.1};
RN [1] {ECO:0000313|EMBL:KOF84092.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF84092.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF84092.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome, telomere
CC {ECO:0000256|ARBA:ARBA00004574}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the telombin family.
CC {ECO:0000256|ARBA:ARBA00008442}.
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DR EMBL; KQ419277; KOF84092.1; -; Genomic_DNA.
DR RefSeq; XP_014775494.1; XM_014920008.1.
DR AlphaFoldDB; A0A0L8H4F7; -.
DR STRING; 37653.A0A0L8H4F7; -.
DR EnsemblMetazoa; Ocbimv22022639m; Ocbimv22022639m.p; Ocbimv22022639m.g.
DR EnsemblMetazoa; XM_014920008.1; XP_014775494.1; LOC106872871.
DR OMA; DETHHEG; -.
DR OrthoDB; 52603at2759; -.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0043047; F:single-stranded telomeric DNA binding; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR CDD; cd04497; hPOT1_OB1_like; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 2.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR028389; POT1.
DR InterPro; IPR032042; POT1PC.
DR InterPro; IPR011564; Telomer_end-bd_POT1/Cdc13.
DR PANTHER; PTHR14513; PROTECTION OF TELOMERES 1; 1.
DR PANTHER; PTHR14513:SF0; PROTECTION OF TELOMERES PROTEIN 1; 1.
DR Pfam; PF02765; POT1; 1.
DR Pfam; PF16686; POT1PC; 1.
DR SMART; SM00976; Telo_bind; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022895};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Telomere {ECO:0000256|ARBA:ARBA00022895}.
FT DOMAIN 7..141
FT /note="Telomeric single stranded DNA binding POT1/Cdc13"
FT /evidence="ECO:0000259|SMART:SM00976"
FT REGION 304..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KOF84092.1"
SQ SEQUENCE 359 AA; 41080 MW; 7C6D1D4BD2FC4BDF CRC64;
KPRTYSYSSL TSLKPNTMVN IYGIVKFFKL PFKTKGTDFM MIVTIVDESI IHTDQKLKCL
LFSYEERCLP EMKIGSIIRF HRLRINLYNG ELQGKSGKGF SWLVIDNQGD GSMITKASRV
NYTFSDADRR KVARLFHIKQ QKQELRCQNL VKLEQLQEGI YFDFLCQVVA VSVVELNVCY
LLQVWDGTHS SCPLFTVEPE ERNLTVKTDM ELKKIAKDRL VDVCVYDDHF EKAATIKPGM
FIKFFNLHCS KRKAPEFVNA STYEKLELVL HQGTSYGRGI KILSETDPEI DDLKKKLEEL
TKNVERTGTS VKRGPKGSHS KGVKKKKVET VSQNTLELTH FGPSCSQPSR DAKQGEILQ
//
