ID A0A0L8H4S8_OCTBM Unreviewed; 492 AA.
AC A0A0L8H4S8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=phenylalanine--tRNA ligase {ECO:0000256|ARBA:ARBA00012814};
DE EC=6.1.1.20 {ECO:0000256|ARBA:ARBA00012814};
GN ORFNames=OCBIM_22023224mg {ECO:0000313|EMBL:KOF83785.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF83785.1};
RN [1] {ECO:0000313|EMBL:KOF83785.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF83785.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF83785.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC Phe-tRNA synthetase alpha subunit type 2 subfamily.
CC {ECO:0000256|ARBA:ARBA00006703}.
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DR EMBL; KQ419376; KOF83785.1; -; Genomic_DNA.
DR RefSeq; XP_014775731.1; XM_014920245.1.
DR AlphaFoldDB; A0A0L8H4S8; -.
DR STRING; 37653.A0A0L8H4S8; -.
DR EnsemblMetazoa; Ocbimv22023224m; Ocbimv22023224m.p; Ocbimv22023224m.g.
DR EnsemblMetazoa; XM_014920245.1; XP_014775731.1; LOC106873038.
DR GeneID; 106873038; -.
DR KEGG; obi:106873038; -.
DR OMA; QIEGWVM; -.
DR OrthoDB; 4619at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0006432; P:phenylalanyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00496; PheRS_alpha_core; 1.
DR Gene3D; 1.10.10.2320; -; 1.
DR Gene3D; 1.10.10.2330; -; 1.
DR Gene3D; 3.30.1370.240; -; 1.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004529; Phe-tRNA-synth_IIc_asu.
DR InterPro; IPR002319; Phenylalanyl-tRNA_Synthase.
DR InterPro; IPR040724; PheRS_DBD1.
DR InterPro; IPR040725; PheRS_DBD3.
DR NCBIfam; TIGR00468; pheS; 1.
DR PANTHER; PTHR11538:SF40; PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT; 1.
DR PANTHER; PTHR11538; PHENYLALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF18552; PheRS_DBD1; 1.
DR Pfam; PF18553; PheRS_DBD3; 1.
DR Pfam; PF01409; tRNA-synt_2d; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 224..475
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 492 AA; 56062 MW; E40A70F85FE2491C CRC64;
MSDLQQSLLS YIDDKDSVDT LQLAQEWNVD HQKIVGVVKS LQALGEIIDV EQKSGKKLEL
TEEGQTICNS GSYEALIYNS IPEGGILQSE IMKNVPNAKI GFNKAMSAGW IRIDKTAEGG
PRIYKKVEKI EDKVQETLKQ LHSLSLPDAQ CKDFKKRKLI VESKVNSFII SKGPNFTLKI
SKPEIDLTPE MIASGSWKTF QFKPYNFNAR GVLPPSGHLH PLLKVRAQYM KIFLEMGFSE
MATNNFVESS FWNFDALFQP QQHPARDAHD TFFISDPMNA HEFPEDYLER VKTVHSEGGY
GSQGYRYNWK IEEAQKNIMR THTTAVSARM LYKLAQEKPF KPAKYFSIDR VFRNETLDAT
HLAEFHQIEG VVIDYNLTLG DLMGVIHKFF SKLGMTKLRF KPAYNPYTEP SMEIFSYHEG
LKKWVEIGNS GVFRPEMLLP MGLPENVSAI AWGLSLERPT MILYGIDNIR DLIGPKINLQ
MVYNNPICRV GI
//
