ID   A0A0L8H882_OCTBM        Unreviewed;       939 AA.
AC   A0A0L8H882;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Glucosidase II subunit alpha {ECO:0000256|ARBA:ARBA00042895};
GN   ORFNames=OCBIM_22020195mg {ECO:0000313|EMBL:KOF85491.1};
OS   Octopus bimaculoides (California two-spotted octopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX   NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF85491.1};
RN   [1] {ECO:0000313|EMBL:KOF85491.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF85491.1};
RC   TISSUE=Gonad {ECO:0000313|EMBL:KOF85491.1};
RA   Tran T., Druce J.;
RT   "MeaNS - Measles Nucleotide Surveillance Program.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Glycan metabolism; N-glycan metabolism.
CC       {ECO:0000256|ARBA:ARBA00004833}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC       {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
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DR   EMBL; KQ418873; KOF85491.1; -; Genomic_DNA.
DR   RefSeq; XP_014774608.1; XM_014919122.1.
DR   AlphaFoldDB; A0A0L8H882; -.
DR   STRING; 37653.A0A0L8H882; -.
DR   EnsemblMetazoa; Ocbimv22020195m; Ocbimv22020195m.p; Ocbimv22020195m.g.
DR   EnsemblMetazoa; XM_014919122.1; XP_014774608.1; LOC106872213.
DR   GeneID; 106872213; -.
DR   KEGG; obi:106872213; -.
DR   OMA; QAGIWYP; -.
DR   OrthoDB; 5480935at2759; -.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0090599; F:alpha-glucosidase activity; IEA:UniProt.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06603; GH31_GANC_GANAB_alpha; 1.
DR   CDD; cd14752; GH31_N; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 2.
DR   Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 2.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR030458; Glyco_hydro_31_AS.
DR   InterPro; IPR048395; Glyco_hydro_31_C.
DR   InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR   InterPro; IPR000322; Glyco_hydro_31_TIM.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR   PANTHER; PTHR22762:SF54; BCDNA.GH04962; 1.
DR   Pfam; PF13802; Gal_mutarotas_2; 1.
DR   Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR   Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR   PROSITE; PS00129; GLYCOSYL_HYDROL_F31_1; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU361185};
KW   Hydrolase {ECO:0000256|RuleBase:RU361185}.
FT   DOMAIN          89..319
FT                   /note="Glycoside hydrolase family 31 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13802"
FT   DOMAIN          381..709
FT                   /note="Glycoside hydrolase family 31 TIM barrel"
FT                   /evidence="ECO:0000259|Pfam:PF01055"
FT   DOMAIN          717..805
FT                   /note="Glycosyl hydrolase family 31 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21365"
FT   REGION          184..220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        196..220
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   939 AA;  108409 MW;  9B9D6C9BDD2088A6 CRC64;
     MALSCTCLIR STMAQHWHVV LYCICLIYSV VAVSRENFKT CEQSGFCKRQ RAVEAGHSSY
     AVLLDSLDLK PSSITLQLVN RKNNVRFKLE LYALAHNMAR IKLNEFSPLK SRYEIPIGDT
     LIKEPVLQNL KLVSKDKNSL ILSFETNHVV ITAEPFRIDF LTNDHPVLSI NSQGLFKFEH
     LRQKQDANPA EPPQEGGESN EEKKENTQEE SKSEPEEPDM WEETFKSFTD SKPNGPTSVG
     IDISFPGFEN VYGIPEHADS FALKSTKSTD PYRLYNLDVF EYELYNPMAL YGSIPVMLAH
     NEERTVGVFW HNAAETWIDI TSNVADKNLF KKMMDYVKGD QEIPQTDTHW FSESGIIDVF
     VMLGPKPRDV FYQYSLLTGT TPLPPLFALA YHQSRWNYND EEDVKNVDNN FDVHDIPYDV
     LWLDIEHTDG KRYFTWDSAK FPNPEDMVRN LSSKGRKLVN VVDPHLKRDD DYSIYKEGKE
     KDIFVKNKDG GVFDGWCWPG SSSWPDFLDP NVREWWASKF DFKEYKGSTK DVFIWNDMNE
     PSVFNGPEIT MPKDLIHVNG WEHRDIHNIY GMHVHRATME GILARSNYQE RSFVLTRAIF
     AGSQRYAAVW TGDNTGEWGH LKMSVPMMLS LNVAGMPFSG ADIGGFFRNP DPELLTRWYQ
     AAAFQPFFRA HAHLDTKRRE PWLLPEMNKN IIRNAIHTRY TFLPYWYTLF RHSEKSGMPV
     MMPLWVEFPE ESSIFKTDDE YLLGPALLVK PVVDPGVAST DVHFPGKGEI WYDIMNFKSF
     AGGQSVQVDA PLDKIPVYIR GGFIIPRKYR MRRSSILMRH DPFSLIVCLD RNDVAKGDLY
     IDDYHSTKYK QAEFAHQEFT FEKNTLSTKL VNPQTTYRTK EWIERIIIAG LEKQPMKPTL
     SVNGSPSKIL ETKYYTETKV LVIRKPGVNI MDNWTITLE
//