ID A0A0L8I309_OCTBM Unreviewed; 1228 AA.
AC A0A0L8I309;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Protein transport protein Sec24B {ECO:0008006|Google:ProtNLM};
GN ORFNames=OCBIM_22036964mg {ECO:0000313|EMBL:KOF95878.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF95878.1};
RN [1] {ECO:0000313|EMBL:KOF95878.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF95878.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF95878.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC {ECO:0000256|ARBA:ARBA00008334}.
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DR EMBL; KQ416666; KOF95878.1; -; Genomic_DNA.
DR RefSeq; XP_014791291.1; XM_014935805.1.
DR RefSeq; XP_014791292.1; XM_014935806.1.
DR AlphaFoldDB; A0A0L8I309; -.
DR STRING; 37653.A0A0L8I309; -.
DR EnsemblMetazoa; Ocbimv22036964m; Ocbimv22036964m.p; Ocbimv22036964m.g.
DR EnsemblMetazoa; XM_014935805.1; XP_014791291.1; LOC106884425.
DR EnsemblMetazoa; XM_014935806.1; XP_014791292.1; LOC106884425.
DR GeneID; 106884425; -.
DR KEGG; obi:106884425; -.
DR OMA; MSAYNPN; -.
DR OrthoDB; 977017at2759; -.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd01479; Sec24-like; 1.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR041742; Sec24-like_trunk_dom.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR006895; Znf_Sec23_Sec24.
DR InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR PANTHER; PTHR13803:SF39; SECRETORY 24AB, ISOFORM A; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR Pfam; PF04810; zf-Sec23_Sec24; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR SUPFAM; SSF82919; Zn-finger domain of Sec23/24; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 564..600
FT /note="Zinc finger Sec23/Sec24-type"
FT /evidence="ECO:0000259|Pfam:PF04810"
FT DOMAIN 637..874
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 879..963
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 974..1074
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT REGION 1..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..261
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..281
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1228 AA; 133907 MW; 043DA0A51C4CCDAA CRC64;
MSAPPMPRKS GPPPGVFGSP QNVPMSNYQP QANVPSGMTS MPPTQLQQPQ QQHPQSQGQL
PPLSNSYNGF SSPPSIGHSQ AMNTVRSGPP RMSSGQSYNY ASSQNVGSFG QYGPSDSGPR
MLVPSSGSAP HPPPMSSQPF VNGPSSMEPN SIAQYPKNSM GPPQNIVPFS SESKPTYPAA
GHPSTTGSMR PPLPSQPLQN QQQHQQIPGY NMGPVNPNTS SAIGSMPPMS RAPRPPLPTS
NMGGIGPPPT SSRPPLLSHA TPPVPDAQYN NSPNPPAVSG QIPGSHMQGG ARPPSITTSL
ATEELPAPYH GQAQYSHQIK NLLSTTSNSG PPSQKSSRAP SPIASQSYDA LEGQFTPSSG
PPMSMPPQSL PSQTGAPPST GRITGKRQYP QMPSQMQSPA HPANMSTSGM PPVYSGSPMH
APQQLQQPPQ QMQQPPQQLQ QSIHPQQPQQ YQPQQQQSSQ YSTSGGMAGL TGGMSNLSTK
DTISDVVDLM QQRKLIGPEG VETPINCLPY EFSKTNASPD IFRCTLNAVP QTAALLTKSR
LPLGVIIHPF KDLTQLPVIT STVIVRCRSC RTYINPFISF VDRTRWKCNL CYRINDLPEE
FSFDPVSRTY GDPQRRPEVR SSTIEFIAPS EYMLRPPQPA VYLFVLDVTY NAIETGYLTV
VCKTLLAELE KLPGDSRTQI GFIAFDRAIH FFNLAEGLSQ PQMLTVSDID DIFLPLPDSL
LVNLHESHDL VQDLLQQLPQ LFENNMETGN ALGATLEASY KLLSPTGGRI TVFQTCLPSA
GPGALQVRED ISKSNKNIPN LGPATDFYKK LALDCSAQQV AIDLFMLNTQ YADIATVACA
SKYSGGCVYH YPSFHSVRNP SLTDKFESDF ARYLYRKIGF EAVMRIRCTR GLSIHTFHGN
FFVRSTDLLS LPNINPDAGF GMQMSIEESL NESNTACFQA ALLYTSSKGE RRIRVHTLCL
PVTTELSAVH AGADQQAIAA LLAKMAVDRT LSSSLGDAQD ALIIAAVDAL SSYASSQSSA
SRIGNLLCPY SLRLLPLYVL SLLKSKAFRS SHVSLDERVC AMEQCKTLPM CYLLQKVYPN
LYPVHNLDDE HVTDRGGNSV PWAPVLQLSA ANLDRHGAYL LDVVDSMILF IGGAISDRFC
QDVFDKPNFS SLCDGLTSLP ERDNPTSERL HLFIYSLMDS RPYGCSFIIL REDSKRKHLF
FQHFVEDRTE STMSYYEFVQ HIQKQAKG
//
