ID A0A0L9V7E3_PHAAN Unreviewed; 683 AA.
AC A0A0L9V7E3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Nucleobase-ascorbate transporter {ECO:0000313|EMBL:KAG2397484.1};
GN ORFNames=HKW66_Vig0142800 {ECO:0000313|EMBL:KAG2397484.1},
GN LR48_Vigan08g142100 {ECO:0000313|EMBL:KOM50594.1};
OS Phaseolus angularis (Azuki bean) (Vigna angularis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3914 {ECO:0000313|EMBL:KOM50594.1, ECO:0000313|Proteomes:UP000053144};
RN [1] {ECO:0000313|Proteomes:UP000053144}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. Jingnong 6 {ECO:0000313|Proteomes:UP000053144};
RX PubMed=26460024; DOI=10.1073/pnas.1420949112;
RA Yang K., Tian Z., Chen C., Luo L., Zhao B., Wang Z., Yu L., Li Y., Sun Y.,
RA Li W., Chen Y., Li Y., Zhang Y., Ai D., Zhao J., Shang C., Ma Y., Wu B.,
RA Wang M., Gao L., Sun D., Zhang P., Guo F., Wang W., Li Y., Wang J.,
RA Varshney R.K., Wang J., Ling H.Q., Wan P.;
RT "Genome sequencing of adzuki bean (Vigna angularis) provides insight into
RT high starch and low fat accumulation and domestication.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:13213-13218(2015).
RN [2] {ECO:0000313|EMBL:KOM50594.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Seedling {ECO:0000313|EMBL:KOM50594.1};
RA Chooi Y.-H.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAG2397484.1, ECO:0000313|Proteomes:UP000743370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaf {ECO:0000313|EMBL:KAG2397484.1};
RA Xiang H.;
RT "Vigna angularis (adzuki bean) Var. LongXiaoDou No. 4 denovo assembly.";
RL Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; JABFOF010000005; KAG2397484.1; -; Genomic_DNA.
DR EMBL; CM003378; KOM50594.1; -; Genomic_DNA.
DR RefSeq; XP_017433532.1; XM_017578043.1.
DR AlphaFoldDB; A0A0L9V7E3; -.
DR STRING; 3914.A0A0L9V7E3; -.
DR EnsemblPlants; KOM50594; KOM50594; LR48_Vigan08g142100.
DR GeneID; 108340572; -.
DR Gramene; KOM50594; KOM50594; LR48_Vigan08g142100.
DR KEGG; var:108340572; -.
DR OMA; VSRHAHM; -.
DR OrthoDB; 345287at2759; -.
DR Proteomes; UP000053144; Chromosome 8.
DR Proteomes; UP000743370; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR11119:SF28; NUCLEOBASE-ASCORBATE TRANSPORTER 12; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053144};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 154..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 500..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 527..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 558..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 613..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 683 AA; 73576 MW; 9D62283E928EBD31 CRC64;
MSNSDSNNRN SLAPSPPEPK PMPPSSWAKK TGFRPKFSGE TNATDSGPIT IPTPNGDIEA
GRVRTPATAN GVAQGDKPPV PVPPRPAMAK KQGDSDGVPK NSIPSTNGQA AAAEQPPRRN
ARHEEVVDGL PVEVDEFVSR HAHMKYELRD SPGLVPIGVY GVQHYLSMLG SLVLIPLVIV
PAMGGTHEET SMVVSTVLFV SGVTTLLHVA FGSRLPLIQG PSFVYLAPAL AIINSPEFQG
LNGNKFKHIM KELQGAIIIG SAFQALLGYT GLMSLLVRLI NPVVVAPTIA AVGLSFYSYG
FSLVGTCIEI GAVQILVAIV FSLYLRKISV LGHRIFLIYA VPLGLAITWA FAFLLTEAGA
YSYKGCDINI PASNMVSEHC RKHFSRMRRC RVDTSQALLS SPWFRFPYPL QWGTPVFHWK
MALVMCVVSL ISSVDSVGTY HASSLLVASR PPTTGVLSRG IGVEGLSSVL AGLWGTGTGS
ITLTENVHTI AVTKMGSRRA VQLGACFLIV LSLVGKVGGF IASIPEVMVA GLLCFMWAML
TALGLSNLRY SEAGSSRNII IVGLSLFFSL SIPAYFQQYG ITPNSNLSVP NYFQPYIVAS
HGPIHSKYGG LNYVLNTLFS LHMVIAFLVA VILDNTVPGS KVERGVYVWS EAEIARREPA
VANDYELPFR IGRIFRWVKW VGL
//
