ID A0A0M0J8F3_9EUKA Unreviewed; 1121 AA.
AC A0A0M0J8F3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Ran-binding protein {ECO:0000313|EMBL:KOO22483.1};
GN ORFNames=Ctob_000317 {ECO:0000313|EMBL:KOO22483.1};
OS Chrysochromulina tobinii.
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Prymnesiales;
OC Chrysochromulinaceae; Chrysochromulina.
OX NCBI_TaxID=1460289 {ECO:0000313|EMBL:KOO22483.1, ECO:0000313|Proteomes:UP000037460};
RN [1] {ECO:0000313|Proteomes:UP000037460}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP291 {ECO:0000313|Proteomes:UP000037460};
RX PubMed=26397803; DOI=10.1371/journal.pgen.1005469;
RA Hovde B.T., Deodato C.R., Hunsperger H.M., Ryken S.A., Yost W., Jha R.K.,
RA Patterson J., Monnat R.J. Jr., Barlow S.B., Starkenburg S.R.,
RA Cattolico R.A.;
RT "Genome Sequence and Transcriptome Analyses of Chrysochromulina tobin:
RT Metabolic Tools for Enhanced Algal Fitness in the Prominent Order
RT Prymnesiales (Haptophyceae).";
RL PLoS Genet. 11:e1005469-e1005469(2015).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOO22483.1}.
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DR EMBL; JWZX01003273; KOO22483.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M0J8F3; -.
DR OrthoDB; 24319at2759; -.
DR Proteomes; UP000037460; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR041389; Importin_rep_6.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF5; IMPORTIN-5 ISOFORM X1; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13646; HEAT_2; 1.
DR Pfam; PF18808; Importin_rep_4; 1.
DR Pfam; PF18829; Importin_rep_6; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000037460};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 354..600
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 413..451
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 927..962
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REGION 827..850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 834..849
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1121 AA; 123431 MW; 17540C3417358949 CRC64;
MALDASMLQQ FEMMLQALLS QDNSIRRQAE EAFEQAKANK DALFSGLVHM LCTNQAEEVR
ALCAVLLRKS VMACATQAQG SLISLLSPAV GQALKSHLLA CIQSEPKKHI RKKVCDAVGQ
LGINLLNADQ QNGWPELLPF MLQGTRSGDA NMHEASLTIF NALADFMCEK MVPYHATLLE
VFRGSLQTDQ PMAVRIAGLK GLASFLLALQ SADTRNHFQE LVPLMQQAIA QALTSGEEES
CRSALEVFVE IAESQPKFLK RHLHEAVNGM VAIASNTSLE DATRHLALEF LLTVAENMTS
AAKKLDRFCE TTVPVALSMM LEIDMNTAEE LAEWEEREED DEDEEITNYD VGEEAIDRLA
IALGGKLMVP VLFEKIQQLI KSPDWKHRHA ALMSISQSGE GCEMAMKANL QQIVTMIVGH
FRDEHPRVRW AAINTVGQMC TDFGPDLQEE LHELVLPALI ATMDDGCKRV QAHAAAAVIN
FCEHCSKPTL KRYLPDLLGK LMVLLQRNVR RVTEQAVTAI ASVADVAEED FAPYYGSFMP
GLKQILQLAG GKQFRMLRGK AMECISLIGV AVGDAAFEPD AKEVMDLIIQ TQQTEALDPD
DPQIQFMLQA CGRICKCLGE KFSPYLPYVI PPLLRSALVD PELHVTDADD EDEVEAEEGM
ESVTVAIRGQ GNKRITIRTS ALEEKATACH MLRTYALELK DAFFPHVADV ARVLVPLIGF
QYMDEVRVNA CHAMPDLLDS AILALQKGAP SATPDVVHQL KGYLYKAVID QLHKEPDTET
LAELLTAWCE IIKHGEECDA AKLTPEELQQ SFEVVKELVV EVIERRDERS KAAGDEEGDD
EEEDAREADA INDENLISTL VECLGTLFKV YGSPLLPLFQ AQLQPIVQAM LQPTAAEPDR
VAALCVFDDI IEHCSADGGA TEYARTLLPA YLQYARDPKP EVRQAAVYGL GVLAACDNGA
AFGAAQQQQA AQVLIEVFEA EQAFDEDNAS ASDNAVSALG KLCARTPEIG AVGWPRWLNV
LPIRADKEEA WKVHQQLVQL VEASNTAVMG ASMERLPDII CIFGEILGTD LIEPGLELRI
THLLKQVRDG LPQVLSALPS HPRFARLKPN QRTQLERALS S
//
