ID A0A0M0K1X7_9EUKA Unreviewed; 721 AA.
AC A0A0M0K1X7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=ATP-dependent DNA helicase {ECO:0000313|EMBL:KOO32582.1};
GN ORFNames=Ctob_014827 {ECO:0000313|EMBL:KOO32582.1};
OS Chrysochromulina tobinii.
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Prymnesiales;
OC Chrysochromulinaceae; Chrysochromulina.
OX NCBI_TaxID=1460289 {ECO:0000313|EMBL:KOO32582.1, ECO:0000313|Proteomes:UP000037460};
RN [1] {ECO:0000313|Proteomes:UP000037460}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP291 {ECO:0000313|Proteomes:UP000037460};
RX PubMed=26397803; DOI=10.1371/journal.pgen.1005469;
RA Hovde B.T., Deodato C.R., Hunsperger H.M., Ryken S.A., Yost W., Jha R.K.,
RA Patterson J., Monnat R.J. Jr., Barlow S.B., Starkenburg S.R.,
RA Cattolico R.A.;
RT "Genome Sequence and Transcriptome Analyses of Chrysochromulina tobin:
RT Metabolic Tools for Enhanced Algal Fitness in the Prominent Order
RT Prymnesiales (Haptophyceae).";
RL PLoS Genet. 11:e1005469-e1005469(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOO32582.1}.
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DR EMBL; JWZX01001734; KOO32582.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M0K1X7; -.
DR OrthoDB; 5884at2759; -.
DR Proteomes; UP000037460; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR Gene3D; 1.10.1600.10; -; 1.
DR Gene3D; 2.40.290.10; -; 1.
DR Gene3D; 1.25.40.240; Ku, C-terminal domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR006164; Ku70/Ku80_beta-barrel_dom.
DR InterPro; IPR036494; Ku_C_sf.
DR InterPro; IPR005161; Ku_N.
DR InterPro; IPR014893; Ku_PK_bind.
DR InterPro; IPR016194; SPOC-like_C_dom_sf.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR12604; KU AUTOANTIGEN DNA HELICASE; 1.
DR Pfam; PF02735; Ku; 1.
DR Pfam; PF03731; Ku_N; 1.
DR Pfam; PF08785; Ku_PK_bind; 1.
DR SUPFAM; SSF101420; C-terminal domain of Ku80; 1.
DR SUPFAM; SSF100939; SPOC domain-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KOO32582.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000037460}.
FT DOMAIN 19..168
FT /note="Ku70/Ku80 N-terminal alpha/beta"
FT /evidence="ECO:0000259|Pfam:PF03731"
FT DOMAIN 251..397
FT /note="Ku"
FT /evidence="ECO:0000259|Pfam:PF02735"
FT DOMAIN 549..689
FT /note="Ku C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08785"
FT REGION 516..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 721 AA; 77051 MW; 87031D951FCDC8D0 CRC64;
MSAASAAKEA LCVVIDVSRH MRPHLDDALE AVRMLVNAKI LFHKQDVVGL VLHGTQATEN
TVAAEYGGDQ YMHITETHAM APVSYRTLEA LDRTAATPVV DPEDSADLID SLCVGMFAVI
AYVKKLKFAK RVILLTDGTS PATAEGEDGD QLDAIARQLK ESQICFEVFG IGIGTVADDA
DDGTAAAEEE DSDPIAAARK ATLRVLRRLE TAVGHEHFKM TPMSDAREAL GALKKRSVRS
STCFRGPLDI GGIGLPVWSW RKVVAATPPS YKTVAKAALD DPTGEGMANP EGTVIVERRQ
LVPSRPDDDV PPDQIISAYR FGKDLVPIDR ADGERLKLGV PSKTLQLFGL VPRADVPRWM
LTSRPECVVP PPEGTGGCDA NKALQALLLV LEEEGLVQAA AELIDAFDLT PDGEGCAAEA
TAARAAGALV GGKEPLKPKQ VYNPRLQRHY QCIQHRARAM IGTSAGGAGG TATASHLPSP
DWRITTPLVP DAAMLQRAAP AIDAFAAACP LSGAVGGKRG RGGRAGATGS GAADAAPPYP
KVARSEEAPV KTFWEMMDDQ AEDRVADALD QMAQMVLDLL RSVGADETDF GRPHGPGQKG
LSCLRELRRA SVREYSAKQF NRVLTQLREL YRDEASGRAF VWRAIVAQIG DPSQLKHGLI
VHEEICADEY GDGLADEETV SREQARAFWQ PLAPAAPDTS PLAAEPLAAV DEMDEDLDAL
E
//
