ID   A0A0M2GS69_9ACTN        Unreviewed;       810 AA.
AC   A0A0M2GS69;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=PAS/PAC sensor protein {ECO:0000313|EMBL:KJK40683.1};
GN   ORFNames=UK15_06460 {ECO:0000313|EMBL:KJK40683.1};
OS   Streptomyces variegatus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=284040 {ECO:0000313|EMBL:KJK40683.1, ECO:0000313|Proteomes:UP000034786};
RN   [1] {ECO:0000313|Proteomes:UP000034786}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-16380 {ECO:0000313|Proteomes:UP000034786};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.;
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJK40683.1}.
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DR   EMBL; JYJH01000003; KJK40683.1; -; Genomic_DNA.
DR   RefSeq; WP_031133372.1; NZ_JYJH01000003.1.
DR   AlphaFoldDB; A0A0M2GS69; -.
DR   STRING; 284040.UK15_06460; -.
DR   PATRIC; fig|284040.3.peg.3349; -.
DR   Proteomes; UP000034786; Unassembled WGS sequence.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00091; PAS; 2.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
FT   DOMAIN          21..58
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          130..200
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          205..256
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   810 AA;  87319 MW;  F6D161F92D85A86C CRC64;
     MIGSASARDE GPPSGGSREH VDEAATARVV VDGRGVVTAW NEGARRLLGY RAPEVVGRHA
     ARLLADAAHT HVPDADALTG LRRWSGTATL LHRDGHRLTV GLLAHHRAND AGDDWLLVSP
     VARPAPTPED DAFVRRSFAQ APYTMALYDT GLRLRWANAD MERVMGLPEE EMRGLRVTEI
     VLDPESERTE EGMRTALETG RLQELGAALR LAGHERESAW SVSLVPVRDS DGRPEGVLLS
     AHDVTEQYLA RQRLVLVDDA SRRIGSTLDL PRTAQELADV AVPRFADFVT VDLLPAIEGG
     EDPPEGAPHG PVRLRRVASQ SVLEGCPETV VQHGTVAAYP EGSTAARCLA AGRPIIEHIT
     PAALEELDRT APQRAERMRQ FGFHSVLAVP MRARGLTLGV ATFSRHRRPK RFAQDDLLLG
     QEITARAAVC IDNARRYTRE RDTSLTLQNS LLPQGLPEQA ALDVASRYLP ASARAGVGGD
     WFDVIPLSGA RVALVVGDVV GHGIQASATM GRLRTAVRTL ADVDLPPDEL LTHLDDQVNR
     LAGGADTMAQ LDGDIGATCL YAVYDPVSRH CTIARAGHPV PALVAPDGTV DFIDVPAGPP
     LGLGGLPFES TELELAEGSL LVLYTDGLVE VRGHDIDEGI AAMREVLRRP AGDLEATCDA
     LLRTLLVDRP SDDVALLVAR TRALDASHVA TWPVPPDPAA VAETRKAACR QLSEWGLEEA
     VFVTELVVSE LVTNAIRYGR PPIELRLIHD RTLICEVSDG STTAPHLRRA RTFDEGGRGL
     LLVAQLTQGW GTRQITNGKI IWAEQSLPAD
//