ID A0A0M2H1D2_9MICO Unreviewed; 452 AA.
AC A0A0M2H1D2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Magnesium and cobalt efflux protein CorC {ECO:0000313|EMBL:KJL37868.1};
GN Name=corC_2 {ECO:0000313|EMBL:KJL37868.1};
GN ORFNames=RS81_02856 {ECO:0000313|EMBL:KJL37868.1};
OS Microbacterium ketosireducens.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=92835 {ECO:0000313|EMBL:KJL37868.1, ECO:0000313|Proteomes:UP000033956};
RN [1] {ECO:0000313|EMBL:KJL37868.1, ECO:0000313|Proteomes:UP000033956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12510 {ECO:0000313|EMBL:KJL37868.1,
RC ECO:0000313|Proteomes:UP000033956};
RA Corretto E.;
RT "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT metal contaminated environments.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJL37868.1}.
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DR EMBL; JYIZ01000056; KJL37868.1; -; Genomic_DNA.
DR RefSeq; WP_045276783.1; NZ_JYIZ01000056.1.
DR AlphaFoldDB; A0A0M2H1D2; -.
DR STRING; 92835.RS81_02856; -.
DR PATRIC; fig|92835.4.peg.2892; -.
DR OrthoDB; 110231at2; -.
DR Proteomes; UP000033956; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF17; UPF0053 INNER MEMBRANE PROTEIN YFJD; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000033956};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 88..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..183
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 202..261
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 270..327
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 452 AA; 48000 MW; 76C3D0DE12D5F9B9 CRC64;
MTAALLLAAA VVLLAFGALM VAVDAALGVT SRADLADLAA GGRNAAALGR IGADPEAHST
AVNFIRVLAE TTAAVLVTVA LVDLFNSIWW AMLAAAVLMT GISYVVVGAS PRSVGRRHAK
GLLRWAAPII RGVRIILGPL AHGLVALGTR ITPGARSSSF ASEEQLLSII DEATENELIE
EDDRELIHSV FDFTDAFVRE VMVPRTDMVT VDASSTTREA MAVFLDKGVS RVPVVDDDAD
DVTGVLYLKD LVQFGFRDEA GWRDAPITRI TRPAVFIPES MKAETLLQQM KRDAVHVCLV
VDEYGGVSGL VTLEDLIEEL VGEIADEYDP RADEVTELAP GHYRVSSRLG LDEVGDLFGL
ELDDEDVDSI GGLLGKALGR IPQPGATADY AGLVMTGGAT RGRGRGIATV FVERSDTADE
AEPAAARHPR TGEIRVVAPR TGETRVVKKG GR
//
