ID A0A0M2K4P2_9MYCO Unreviewed; 703 AA.
AC A0A0M2K4P2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Acyl-CoA dehydrogenase {ECO:0000313|EMBL:KKF02147.2};
GN ORFNames=WN67_10060 {ECO:0000313|EMBL:KKF02147.2};
OS Mycolicibacterium obuense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1807 {ECO:0000313|EMBL:KKF02147.2, ECO:0000313|Proteomes:UP000034150};
RN [1] {ECO:0000313|EMBL:KKF02147.2, ECO:0000313|Proteomes:UP000034150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UC1 {ECO:0000313|EMBL:KKF02147.2,
RC ECO:0000313|Proteomes:UP000034150};
RA Greninger A.L., Cunningham G., Chiu C.Y., Miller S.;
RT "Genome sequence of Mycobacterium obuense UC1.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the acyl-CoA dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009347}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF02147.2}.
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DR EMBL; LAUZ02000021; KKF02147.2; -; Genomic_DNA.
DR RefSeq; WP_046676554.1; NZ_LAUZ02000021.1.
DR AlphaFoldDB; A0A0M2K4P2; -.
DR STRING; 1807.MOBUDSM44075_00320; -.
DR PATRIC; fig|1807.13.peg.2272; -.
DR OrthoDB; 3964153at2; -.
DR Proteomes; UP000034150; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.540.10; Acyl-CoA dehydrogenase/oxidase, N-terminal domain; 2.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 2.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR013786; AcylCoA_DH/ox_N.
DR InterPro; IPR037069; AcylCoA_DH/ox_N_sf.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR PANTHER; PTHR43292; ACYL-COA DEHYDROGENASE; 1.
DR PANTHER; PTHR43292:SF4; ACYL-COA DEHYDROGENASE FADE34; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 2.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR Pfam; PF02771; Acyl-CoA_dh_N; 2.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630}.
FT DOMAIN 6..89
FT /note="Acyl-CoA dehydrogenase/oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02771"
FT DOMAIN 202..334
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
FT DOMAIN 377..450
FT /note="Acyl-CoA dehydrogenase/oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02771"
FT DOMAIN 454..548
FT /note="Acyl-CoA oxidase/dehydrogenase middle"
FT /evidence="ECO:0000259|Pfam:PF02770"
FT DOMAIN 560..699
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
SQ SEQUENCE 703 AA; 74019 MW; 896EF85BDC95360F CRC64;
MPATISDEQS AARELVRDWA AGSTSLEAVR DVEQGAPDAW RAPFDALAAL GIFGVALPEE
LGGADGTVAD LCAMLEEAAA GLIPGPVATT ALATLVLDGA QGDLVEALAS GQRTAGVALR
AELTLTGERV SGTAATVLGA TADGVLLLPA GDTWVLLDAT ADGVVVERRK ATDFSRPLAR
VTVDGAPATT LDVPAQRVVD LAATVAAAEA AGVARWLLTT ATEYAKVREQ FGKPIGSFQA
IKHMCAEMLL RSEQASVAAA DAARAAGESD DQQLSIAAAL AASVGIEAAT ANAKDCIQVL
GGIGITWEHD AHLYLRRAYG IGQFLGGRSH WLRRVAALTQ QGVRRDLHID LASVADLRPE
IASAVADVAA APQDRRQVVM AETGLLAPHW PRPHGRDAGP AEQLLIDQEL AAAGVTRPDL
VIGWWAVPTI LEHGSAAQVE QFVPPTLRGE LQWCQLFSEP GAGSDLAALR TKAVRAEGGW
KLTGQKVWTS AAQKAHWGVA LARTDPDAPK HKGITYFLID MTSPGIVIRP LREITGDELF
NEVFFDDVFV PDEMVVGAVD DGWKLARTTL ANERVAMAQG TALGNPMEEL LRALSEADVD
DAQQDRLGAL ICTAQVGSLL DQRIAQLAVG GRDPGPQASA RKLIGVRYRQ ALAEFRMELS
DGAGAVENQQ VHDFLNTRCL TIAGGTEQIL LTMAGERLLG LPR
//
