ID A0A0M3I150_ASCLU Unreviewed; 609 AA.
AC A0A0M3I150;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 2.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Regulator of G-protein signaling 7 {ECO:0000313|WBParaSite:ALUE_0000995301-mRNA-1};
OS Ascaris lumbricoides (Giant roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX NCBI_TaxID=6252 {ECO:0000313|Proteomes:UP000036681, ECO:0000313|WBParaSite:ALUE_0000995301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ALUE_0000995301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (MAY-2016) to UniProtKB.
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DR AlphaFoldDB; A0A0M3I150; -.
DR WBParaSite; ALUE_0000995301-mRNA-1; ALUE_0000995301-mRNA-1; ALUE_0000995301.
DR Proteomes; UP000036681; Unplaced.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd00068; GGL; 1.
DR CDD; cd08705; RGS_R7-like; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.196.10; -; 2.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR034483; RGS_Egl-10.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR024066; RGS_subdom1/3.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF6; LP21163P; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00631; G-gamma; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 1.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 37..112
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 398..513
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 259..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 68993 MW; 450989A02B2099B9 CRC64;
MAIPRLRANA SNEERMVHPN HMIYQKMENL VQTMLDPENG VPIKTVKSFL SKVPSVFTGQ
DLIAWIMKNM QMTDLADALH LAHLIASHGY LFQIDDHVLT VKNDGTFYRF QTPYFWPSNC
WEPENTDYAV YLCKRTMQNK AHLELEDFEA ENLAKLQKMF SRKWEFVFMQ AEAQYKVDKK
RDRQERQILD SQERAFWDVH RPVPGCVNTT EVDFRKLSRS GRPKYSSSGH AALNAAASSS
SISSPYSTSA VAAHAAQVPS CSGSGANGAP NTHGSQMSPS VSPQPGESTS TFARHYNYSQ
RPGMRRCTQV QDTLKQEINV LQARLTKNVL KTSKVIENYL QYFEHRRVFD PFLTALGTAA
DPFQGQPNPW LSDTVDFWQH DKITGDISMR RLKLWEESFE ELLCDQLGRD TLQKFLDKEY
SGENLRFWWQ VQKLRKCACR MVPVLVTEIY NEFIDSNATS PVNIDCKVME TTEDNLKNPN
RWSYDEAADH IFCLMKNDSY QRFLRSDIYR DLLNQSKKKT SAPFSSLIAR KTSRKVSRSL
RNVSGIASGG SAASLSAAVP VKVSRDIGIR FPNLPGFSSN TVRRDAQLTA SSVNTATATS
SSPSTTAIT
//
