ID A0A0M6XMX5_9RHOB Unreviewed; 612 AA.
AC A0A0M6XMX5;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Cobalt-precorrin-3B C(17)-methyltransferase {ECO:0000313|EMBL:CTQ31561.1};
DE EC=2.1.1.- {ECO:0000313|EMBL:CTQ31561.1};
GN Name=cbiH {ECO:0000313|EMBL:CTQ31561.1};
GN ORFNames=JAN5088_00319 {ECO:0000313|EMBL:CTQ31561.1};
OS Jannaschia rubra.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Jannaschia.
OX NCBI_TaxID=282197 {ECO:0000313|EMBL:CTQ31561.1, ECO:0000313|Proteomes:UP000048908};
RN [1] {ECO:0000313|EMBL:CTQ31561.1, ECO:0000313|Proteomes:UP000048908}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 5088 {ECO:0000313|EMBL:CTQ31561.1,
RC ECO:0000313|Proteomes:UP000048908};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
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DR EMBL; CXPG01000009; CTQ31561.1; -; Genomic_DNA.
DR RefSeq; WP_055681031.1; NZ_FOOS01000001.1.
DR AlphaFoldDB; A0A0M6XMX5; -.
DR STRING; 282197.SAMN04488517_10199; -.
DR OrthoDB; 9772960at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000048908; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11646; Precorrin_3B_C17_MT; 1.
DR Gene3D; 3.40.50.11220; -; 1.
DR Gene3D; 3.30.420.180; CobE/GbiG C-terminal domain; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR021744; CbiG_N.
DR InterPro; IPR006363; Cbl_synth_CobJ/CibH_dom.
DR InterPro; IPR002750; CobE/GbiG_C.
DR InterPro; IPR036518; CobE/GbiG_C_sf.
DR InterPro; IPR038029; GbiG_N_sf.
DR NCBIfam; TIGR01466; cobJ_cbiH; 1.
DR PANTHER; PTHR47036; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR47036:SF1; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF01890; CbiG_C; 1.
DR Pfam; PF11760; CbiG_N; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF159672; CbiG N-terminal domain-like; 1.
DR SUPFAM; SSF159664; CobE/GbiG C-terminal domain-like; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CTQ31561.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000048908};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CTQ31561.1}.
FT DOMAIN 48..127
FT /note="Cobalamin synthesis G N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11760"
FT DOMAIN 210..329
FT /note="CobE/GbiG C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01890"
FT DOMAIN 346..562
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 612 AA; 63155 MW; 03D38926D2EBB465 CRC64;
MALNPVVLCL NAAGEDVARR IAVALDCPLH GRAGRTAASV TFPDALVHVR DLFAAGHSVI
GVCAAGILIR AVAPLLADKT AEPPVIAVSD DGRVVVPLLG GHRGANRLAR TIADALGGTA
AVTTAGDVAL GVALDEPPEG WVLANPGAAK GAMAALLSGG GARLTGEAAA EAQWLHDLPQ
GAAVTIACTL RPPRADETVP DLLFHPQRAA LGVGASRDCP PEELIALVDG LLADADVAPA
AIAGIFTADI KADEGAVLAL SAHLGVPVRY FNAEELEAAT PRTRTPSDVV FAEIGSHGVA
ENAALLGAGD EAHLTHPKRK SAMATAALAL SPHPVATLPG RARGRVSIVS IGPGQSAWRT
PEASRLIAEA EELVGYSLYI DLLGPLAAGK PRADFPLGGE EARCRHALEQ AGEGRNVALV
CSGDAGIYAM GALVFELMDR DPAATDALTP AARRVEIVCT PGVSALQAAA ARAGAPLGHD
FCAISLSDLL TPREDIVARL HAAARGDFVI AFYNPVSKRR RTLLALARDI LLEHRPADTP
VLLASSLGRP EESLRHRRLA DLRVEEVDML TVVLVGSSQT RLTRTGDGPR MYTPRGYARK
MAGGDLARGA AT
//
