ID A0A0M8MPA9_9BASI Unreviewed; 551 AA.
AC A0A0M8MPA9;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Carboxypeptidase {ECO:0000256|RuleBase:RU361156};
DE EC=3.4.16.- {ECO:0000256|RuleBase:RU361156};
GN ORFNames=Malapachy_2994 {ECO:0000313|EMBL:KOS16516.1};
OS Malassezia pachydermatis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX NCBI_TaxID=77020 {ECO:0000313|EMBL:KOS16516.1, ECO:0000313|Proteomes:UP000037751};
RN [1] {ECO:0000313|EMBL:KOS16516.1, ECO:0000313|Proteomes:UP000037751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 1879 {ECO:0000313|EMBL:KOS16516.1,
RC ECO:0000313|Proteomes:UP000037751};
RA Triana S., Ohm R., Gonzalez A., DeCock H., Restrepo S., Celis A.;
RT "Draft Genome Sequence of Malassezia furfur CBS1878 and Malassezia
RT pachydermatis CBS1879.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a diacylglycerol + H2O = a fatty acid + a monoacylglycerol +
CC H(+); Xref=Rhea:RHEA:32731, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17408, ChEBI:CHEBI:18035, ChEBI:CHEBI:28868;
CC Evidence={ECO:0000256|ARBA:ARBA00043665};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a monoacylglycerol + H2O = a fatty acid + glycerol + H(+);
CC Xref=Rhea:RHEA:15245, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17408, ChEBI:CHEBI:17754, ChEBI:CHEBI:28868;
CC Evidence={ECO:0000256|ARBA:ARBA00043831};
CC -!- SIMILARITY: Belongs to the peptidase S10 family.
CC {ECO:0000256|ARBA:ARBA00009431, ECO:0000256|RuleBase:RU361156}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOS16516.1}.
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DR EMBL; LGAV01000001; KOS16516.1; -; Genomic_DNA.
DR RefSeq; XP_017994148.1; XM_018137475.1.
DR AlphaFoldDB; A0A0M8MPA9; -.
DR GeneID; 28729351; -.
DR VEuPathDB; FungiDB:Malapachy_2994; -.
DR OrthoDB; 1647009at2759; -.
DR Proteomes; UP000037751; Unassembled WGS sequence.
DR GO; GO:0004185; F:serine-type carboxypeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001563; Peptidase_S10.
DR InterPro; IPR018202; Ser_caboxypep_ser_AS.
DR PANTHER; PTHR11802:SF64; CARBOXYPEPTIDASE 2-RELATED; 1.
DR PANTHER; PTHR11802; SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE; 1.
DR Pfam; PF00450; Peptidase_S10; 1.
DR PRINTS; PR00724; CRBOXYPTASEC.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00131; CARBOXYPEPT_SER_SER; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645,
KW ECO:0000256|RuleBase:RU361156};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361156};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU361156};
KW Reference proteome {ECO:0000313|Proteomes:UP000037751};
KW Signal {ECO:0000256|RuleBase:RU361156}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|RuleBase:RU361156"
FT CHAIN 19..551
FT /note="Carboxypeptidase"
FT /evidence="ECO:0000256|RuleBase:RU361156"
FT /id="PRO_5006517802"
SQ SEQUENCE 551 AA; 61129 MW; 4958144D0D06C155 CRC64;
MLLYSIVALA TSITAVSAQF VKPPTDLKKV SGHAGTTVRY KEVPAGICET TEGVKSYSGY
VDTEKDEHIF FWYFESRKDP KNAPLTVWFN GGPGSSSMIG LFQEVGPCGI YPNGTLYNNE
YAWNSESNLL IVDQPVTTGF SYSEVGPVIM DTRGIVVKEL EDNKCPDDTH FFETCATLSL
PSKTKAPKST SQAAPAMWKT VQGFLGAFPE LENAPITIAT ESYGGHYAPT FATYFLEQND
KNVEGAILLN LKSVMIGNGW YDPKVQYMAF YNFTVSPGNT YDLKPFSKEK GEDLYTQVFG
HGMCLDLIED CYRTNSASVC RKADGFCASS VEQFLTRHAH RDEYDIRQVD PDRFPYSRYA
SYLNEAHVLK AIGAFQNYTE SSDLIWKSFS KTGDDARRRG SISKLRELVK RGITVTLYAG
DADYNCNWLG GEIVAEKVGG ASFSKAGYQN ITSKNKDVPG QVKQHGRFSF ARIYYSGHEV
PFYQPIAASE LHHRTVHGLD LATGQEAVSD GYVTKGSPKS EFREGGDTVQ HHIAKTGSLY
DFKKHIPVKP N
//
