ID A0A0M8QD00_9ACTN Unreviewed; 389 AA.
AC A0A0M8QD00;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cysteine desulfurase {ECO:0000313|EMBL:KOT27526.1};
GN ORFNames=ADK41_36375 {ECO:0000313|EMBL:KOT27526.1};
OS Streptomyces caelestis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=36816 {ECO:0000313|EMBL:KOT27526.1, ECO:0000313|Proteomes:UP000037773};
RN [1] {ECO:0000313|EMBL:KOT27526.1, ECO:0000313|Proteomes:UP000037773}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-24567 {ECO:0000313|EMBL:KOT27526.1,
RC ECO:0000313|Proteomes:UP000037773};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. NifS/IscS subfamily.
CC {ECO:0000256|ARBA:ARBA00006490}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOT27526.1}.
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DR EMBL; LGCN01000265; KOT27526.1; -; Genomic_DNA.
DR RefSeq; WP_030828771.1; NZ_LGCN01000265.1.
DR AlphaFoldDB; A0A0M8QD00; -.
DR PATRIC; fig|36816.3.peg.7896; -.
DR OrthoDB; 9808002at2; -.
DR Proteomes; UP000037773; Unassembled WGS sequence.
DR GO; GO:0031071; F:cysteine desulfurase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR Gene3D; 1.10.260.50; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR016454; Cysteine_dSase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11601:SF34; CYSTEINE DESULFURASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF005572; NifS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000037773}.
FT DOMAIN 3..372
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 389 AA; 40335 MW; 655DF3CCB583B234 CRC64;
MAYLDHAATT PMLPEAVEAL AAHLGVTGNA SSLHAAGRRA RRTVEEARET LAEALGARPS
EIVLTSGGTE ADNLAVKGLY WSRRDADPAR TRVLASPVEH HAVLDAVHWL GEHEGATVEY
LPVDPHGRVH PDALREAIAR NPDDVALATV MWANNEIGTI LPVRELAGIA AEFGVPLHSD
AVQAFGQVPV DFAASGLAAM TVSGHKIGGP YGIGALLLGR EHTPVPVLHG GGQERHVRSG
TLDVPAVAAF ATAGRLAAER QEWFAREIGR LRDDLVAAVR EAVPDAVLGG DPAPGGRLPA
NAHFTFPGCE GDSLLLLLDA QGIECSTGSA CTAGVAQPSH VLLATGVEPD LARGTLRFSL
GHTSTEADVE AVAKAIGPAV ERARAAGLS
//
