ID A0A0M8TAD3_9ACTN Unreviewed; 868 AA.
AC A0A0M8TAD3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=ADK57_45300 {ECO:0000313|EMBL:KOU55199.1};
OS Streptomyces sp. MMG1533.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU55199.1, ECO:0000313|Proteomes:UP000037741};
RN [1] {ECO:0000313|Proteomes:UP000037741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU55199.1}.
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DR EMBL; LGDG01000286; KOU55199.1; -; Genomic_DNA.
DR RefSeq; WP_053755626.1; NZ_LGDG01000286.1.
DR AlphaFoldDB; A0A0M8TAD3; -.
DR STRING; 1415546.ADK57_45300; -.
DR PATRIC; fig|1415546.3.peg.9748; -.
DR OrthoDB; 9805696at2; -.
DR Proteomes; UP000037741; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProt.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR PANTHER; PTHR47963:SF8; ATP-DEPENDENT RNA HELICASE DEAD; 1.
DR PANTHER; PTHR47963; DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KOU55199.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000037741}.
FT DOMAIN 3..186
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 215..367
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 373..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 789..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 845..868
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..458
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..676
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..808
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 848..862
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 868 AA; 91596 MW; 6070F63877BF74FA CRC64;
MTLPVALTGT DVIGQAKTGT GKTLGFGLPL LERVTVPADV EAGRAKPEDL TDAPQALVVV
PTRELCTQVT NDLLTAGKVR NVRVLAIYGG RAYEPQVEAL KKGVDVIVGT PGRLLDLAGQ
KKLNLKHIKA LVLDEADEML DLGFLPDVEK IINMLPARRQ TMLFSATMPG AVIGLARRYM
SQPTHISATA PDDAGKTVAN TKQHIYRAHN MDKPELVARI LQAEGRGLVM VFCRTKRTAA
DLADQLQQRG FASGAVHGDL GQGAREQALR AFRNGKVDVL VCTDVAARGI DVEGVTHVIN
YQSPEDEKTY LHRIGRTGRA GAKGIAITLV DWDDIPRWQL INKALDLGFN DPPETYSTSP
HLFEELSIPA GTKGVLPRSE RTRAGLGAEE LEDLGETGGR GARGRGDRGG RGDRDSRGDR
GGRGDRDSRG DRGGRGDRDS RGGREESRSA EDERSARTPR RRRRTRNGAP LDTTAPAGTA
PTEGVAAPQE TTAAEDATAT RTPRRRRRTR GAASETMPAT AAVTVEPTVS EVAPVTEAAE
AAVATAEGTV AVDAAETAAK PRRRRTRKSA ETAVDTAEST TTETVSQTPA APEPEAPVAA
PRRRTRKAAA APAAEVAVDT AEGTGTSEAE AAEVKPRRRT RKTTAAAPAE APAEAALDTA
EAVEAKPRRR TRKAVATEPV AEIPAQTAPE AAEVKPRRTR KAAATAATAV DTAEAVEAKP
RRTRKATAAA AEAAVDTAEG TATKPRRTRK TAAAAPAEAA LDTAEAVEAK PRRTRKTAAA
APAEAAVDTA EAVEAKPRRT RKTAAAKAVE GDVVEAAAEA KPRRRTRKAA EPDVAVAAIP
AQAVAEEKVA APRRRTRKAA AATEPTES
//
