ID A0A0M8U043_9ACTN Unreviewed; 622 AA.
AC A0A0M8U043;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN ORFNames=ADK57_00555 {ECO:0000313|EMBL:KOU78083.1};
OS Streptomyces sp. MMG1533.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU78083.1, ECO:0000313|Proteomes:UP000037741};
RN [1] {ECO:0000313|Proteomes:UP000037741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 33 family.
CC {ECO:0000256|ARBA:ARBA00009348}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU78083.1}.
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DR EMBL; LGDG01000001; KOU78083.1; -; Genomic_DNA.
DR RefSeq; WP_053747440.1; NZ_LGDG01000001.1.
DR AlphaFoldDB; A0A0M8U043; -.
DR STRING; 1415546.ADK57_00555; -.
DR PATRIC; fig|1415546.3.peg.116; -.
DR Proteomes; UP000037741; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd00110; LamG; 1.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006558; LamG-like.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR SMART; SM00282; LamG; 1.
DR SMART; SM00560; LamGL; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000037741};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..622
FT /note="exo-alpha-sialidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005824552"
FT DOMAIN 458..597
FT /note="LamG-like jellyroll fold"
FT /evidence="ECO:0000259|SMART:SM00560"
FT DOMAIN 458..592
FT /note="Laminin G"
FT /evidence="ECO:0000259|SMART:SM00282"
SQ SEQUENCE 622 AA; 66372 MW; 84EA2D9A04B26A24 CRC64;
MPARLRAHPG STTLTAVIAT AALIASPTPV HAQSRAAAPE FEQQVLFKAS QDSGYACFRI
PAIVRTAGGT LLAFAEGRVL NCGDAADIDV VLKRSTDGGR TWGPLQVVNE GDGDTHGNPA
PIVDRNTGRV LLAETYNTGR TDSGGCSAPC DRTPHLQYSD DDGLTWSTPR DLSAEILPAH
WNSWYATGPV HGIQLTRGAH AGRLVFGVNT ETWNGARVTT NHAALIVSDD GGEHWKVGAT
DSWPSAENGT VRQRPSELTL TERTDGAVLV SGREQGGTDI GHRAQAVSLD GGTSFTAPFH
GLPDLYAPQV QCATLPFGDR LLLSCPGDPD RRRTMMIRSS YDGGATWDSV DRGTVVTTDW
SGYSDLAPVD DDTVGLLYEG GAVDARDEIR FARFTEDWLQ ARRGPDPTTA DLAPGARNAT
VLGGPLVTDG VSGGALEFDG ADDAVRLPYR EQLALDTKEF TASLRFRYTA TTGEQPLLWM
GGVGNSQPQV WLRGEPAGNR VRGRITVRDG ARTVRTASVT TTGAYNDGRW HRLALRRGGG
RLTLFIDGTA IGAADVAGSV SRNGPFGVHI GQRMDSRAFF TGAIDDVHVW DRALTDEEIE
AGSAPVGNTV LWLPMDHVSD NR
//
