ID A0A0M8UY77_9ACTN Unreviewed; 1101 AA.
AC A0A0M8UY77;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Regulator {ECO:0000313|EMBL:KOV53246.1};
GN ORFNames=ADL00_35060 {ECO:0000313|EMBL:KOV53246.1};
OS Streptomyces sp. AS58.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519489 {ECO:0000313|EMBL:KOV53246.1, ECO:0000313|Proteomes:UP000037758};
RN [1] {ECO:0000313|EMBL:KOV53246.1, ECO:0000313|Proteomes:UP000037758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AS58 {ECO:0000313|EMBL:KOV53246.1,
RC ECO:0000313|Proteomes:UP000037758};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV53246.1}.
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DR EMBL; LGDU01000377; KOV53246.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8UY77; -.
DR PATRIC; fig|1519489.3.peg.7883; -.
DR Proteomes; UP000037758; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 4.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000037758};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..97
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 971..1004
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 1..97
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 1101 AA; 120210 MW; E8DA758AB1732A2C CRC64;
MLRFEVLGPL RAWRGRTPLE LGPVKRQAVL AALLLRRGAL ASHEWLLDAV WGSEPPPGGR
KVLPTHVNSL RRTLDPEGTQ PAESLIRSGK GWYRFVVDEV RLDTADLEER GDTALRTVAS
GDLATASEEL AFAMGLFRGE PLAGLPGPFA HDERQRWEER RRTLRLERLK CLVLLGRYGE
ALDDLGGVPA SSVADRYDES LTALRVRALY GCGRQAEALG AYEDMRVRLR DELGADPGEN
LRRVHEAVLH QDDAFLLRPP TPPSPAPATL RPSAVPAELP HDTPGFAGRT GELARLHALL
PREQERAEAN TVVISAIGGA AGIGKTALAV RWAHQVRDLF PDGQLYINLH GFDHHRQPVE
PGEALQLLLR SLGLAASEIP ANHEAQGRMY RTRLAGRRML VLLDNAASAE QVRPLLPGSP
GCIVVVTSRN RLGDLVAHDG AHALPLDLLQ PDEARALLSR ALGADRVASD ELAVGELIRL
CGSLPLALRV AAARLAGDPA LRTADLVAEM TEGSRLEALE PEGEADSPLR TAFSVSYRVL
APGARRLFRL LGLFPGAEFT AEIASGLLDA PLSQARRLLG ALAAAHLVEP VTVGRYRFHD
LLREYARERG LLEETDADRG AALERLLIWY LNATRATAGT WLFPELPPSL HPGEHPGMPS
AVTSREWLDA ERANLLAVIN HAAHHGPRPV AWHLTSALFG NFWVHLPRKT WQATAETALD
AAEAEGDLFG QAAMHTGLMV VRWERGRAGQ AMEHATRVLN IGRELGWTTG EAAGLGLRGF
ARWSMARLES AYDDFTAGLR MFRENGNRYF DGFGVVGLGM TCWDLGRLSE AASRLEVALS
HSAELRGWND SMTLQILGRV YWELGRFTDG LQVLGPAVTF DKRAGYRDGR AMMLDTIAKI
NVELGRYDEG LEQAERALAM VKDVGRIWIQ ASIPHTVAAA HRKLGRPDRA LRADEQALAL
ARKGVLKRAE ADSLLSLSLT HHQLGRYDEA RAHAEQALSL ARDHSFRVVE GQALTALFAV
TARSESAESE EGNATAVKLG QEALSVHRET GHRLGEARTL IALACAVQRT DTAAAELMRQ
QARDVFSAMG VPSTEYEGRE D
//
