ID A0A0M8VVE3_9ACTN Unreviewed; 1102 AA.
AC A0A0M8VVE3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Regulator {ECO:0000313|EMBL:KOV71227.1};
GN ORFNames=ADK64_01475 {ECO:0000313|EMBL:KOV71227.1};
OS Streptomyces sp. MMG1121.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415544 {ECO:0000313|EMBL:KOV71227.1, ECO:0000313|Proteomes:UP000037687};
RN [1] {ECO:0000313|Proteomes:UP000037687}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1121 {ECO:0000313|Proteomes:UP000037687};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV71227.1}.
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DR EMBL; LGDV01000001; KOV71227.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8VVE3; -.
DR STRING; 1415544.ADK64_01475; -.
DR PATRIC; fig|1415544.3.peg.309; -.
DR Proteomes; UP000037687; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000037687};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 4..104
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 4..104
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 1102 AA; 118956 MW; 698198667CFDA714 CRC64;
MTTDGIRASG DNGPVRLSLL GTTQVLRPDG TSVPVGGARL RALLTVLALR TGRTVPVGVL
VDEVWGADPP ADAAGALQAL VGRLRRALGA DTVASADGGY RLAVASDDID LTRFERLTGD
GLRALDDDPA KAAALLDDAL ALWRGPALAD LPGRTAEAAR WETRRLDALR ARHTAALALG
QAEHALPELT ALCDGHPLDE PLQALRLRAL RDAGRPAQAL AAYEDVRRLL VDRLGVDPGP
ELRALHTELL TAQSPEHPAS AKPRELLPAV GNLPARLTSF VGREADIDAI GADLAGARLV
TLLGPGGAGK TRLSQEAAEA VRHTVRDGVW LAELAPVDDP EAVPQAVLTA IGARETVLHG
AGVESMRAVT DRHDEPLERL LEHCARRRMV IILDNCEHVV EAAATLVARL LARCPGLVVL
ATSREPLGVP GELVRPVEPL PEPVALRLLA ERGAAARPGF RTEDDPEACA EICRRLDGLP
LAIELAAARL RMLTPRQIAA RLDDRFRLLT SGSRTVLPRQ QTLRAVVDWS WDLLGAHERD
VLARLSVFAG GCDLAAAEAV CGPVALDALG SLVDKSLVVA APSGESGMRY RLLETVAEYA
AERLAESGHR TEAERAHLVY YRELARTTDP LLRGREQRTA IDRFQLEYEN LRTALRHAVA
LGDEQEALCL VLSLLWFWQM RDQRIETRTW CREVMALGPD PFAAPVRPAR PVWHRCTDTP
PPYTGEVLAE ARRGLHLAHL SCMETELEAW QTPAAQAKLR AVTEVYEPGL PQTCRAPGVL
WFFAVMLTGG TEQLRTIIDA TVQTCRDTPG YEWELAGALQ TRANVLANRT AWAGDAYRDA
DEALEIYRRL GDAWGTAEAL SARGEAHESR GAYRAAGADY QAAIEYAERL GARAQTAILG
ARLGNVLMEV GELERGERML REVIAGRAGA HSEAMPAARL FLACWLGLTD RTGEAREQLR
LLREEFVIAH FVVFDAMILN QEAWLDALDQ RPEEALERSR RALRLSRDPL SEMVTPQMPS
FCLGVAALAL AALDGGSRAA DGARCLGASD ALLPAGHVPS GVERRVHDRI EARLREQLDA
AGFAAAYAEG GGLSLAEATA LV
//
