ID A0A0M8W8A6_9NOCA Unreviewed; 501 AA.
AC A0A0M8W8A6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN ORFNames=ADL03_39045 {ECO:0000313|EMBL:KOV78877.1};
OS Nocardia sp. NRRL S-836.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1519492 {ECO:0000313|EMBL:KOV78877.1, ECO:0000313|Proteomes:UP000037746};
RN [1] {ECO:0000313|Proteomes:UP000037746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-836 {ECO:0000313|Proteomes:UP000037746};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV78877.1}.
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DR EMBL; LGDY01000141; KOV78877.1; -; Genomic_DNA.
DR RefSeq; WP_053738647.1; NZ_LGDY01000141.1.
DR AlphaFoldDB; A0A0M8W8A6; -.
DR STRING; 1519492.ADL03_39045; -.
DR PATRIC; fig|1519492.3.peg.8330; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000037746; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07099; ALDH_DDALDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492};
KW Reference proteome {ECO:0000313|Proteomes:UP000037746}.
FT DOMAIN 14..467
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 247
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 281
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 501 AA; 53285 MW; EED43AF72A1183C5 CRC64;
MTQTASDSTL SADGEQRRFA SLDPRTGEVV AHHPVHTAAE VEDAVVSARE AAQWWAGLGF
EGRKTKLDAW RKILSQRADE LVSLISAETG KPADDSRVEI ALVMDHLHWA SRQAGRVLGK
RRVSAGMLMF NHTASLEYRP LGVIGVIGPW NYPAHTPMGS ISYALAAGNA VVFKPSEFTP
GVGTFLASTF TEAVPEYPVF QVVTGFGETG AALCAAGVDK IAFTGSTRTG KKVMAACATT
LTPVLVECGG KDALIVDSDA DLHAAAEAAI WGAVSNAGQT CAGVERVYVA EEVADRFIEI
AVKRARKLKP GGEPNANLGP ITMPAQVEII REHVRDALDR GGKALVGGAD SIRPPYVEPV
VLTDVPEDSL AVTEETFGPT VVINRVPNAL EGVRLANRSK YGLGAAVFSK SRGEELAREL
RVGMVSINSV LTYAAVPGLP FGGVGDSGFG RIHGEDGLRE FAYAKAVTKQ RFKAVIDMTT
FDRSSLAGKQ MLRLARMLFG R
//
