ID A0A0M8W8K4_9NOCA Unreviewed; 375 AA.
AC A0A0M8W8K4;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=citrate synthase (unknown stereospecificity) {ECO:0000256|ARBA:ARBA00012972};
DE EC=2.3.3.16 {ECO:0000256|ARBA:ARBA00012972};
GN ORFNames=ADL03_31760 {ECO:0000313|EMBL:KOV80680.1};
OS Nocardia sp. NRRL S-836.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1519492 {ECO:0000313|EMBL:KOV80680.1, ECO:0000313|Proteomes:UP000037746};
RN [1] {ECO:0000313|Proteomes:UP000037746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-836 {ECO:0000313|Proteomes:UP000037746};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC {ECO:0000256|ARBA:ARBA00005163}.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|RuleBase:RU003406}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV80680.1}.
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DR EMBL; LGDY01000121; KOV80680.1; -; Genomic_DNA.
DR RefSeq; WP_053737245.1; NZ_LGDY01000121.1.
DR AlphaFoldDB; A0A0M8W8K4; -.
DR STRING; 1519492.ADL03_31760; -.
DR PATRIC; fig|1519492.3.peg.6819; -.
DR OrthoDB; 9800864at2; -.
DR UniPathway; UPA00223; -.
DR Proteomes; UP000037746; Unassembled WGS sequence.
DR GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR041657; HTH_17.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF4; CITRATE SYNTHASE, PEROXISOMAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR Pfam; PF12728; HTH_17; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000037746};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003406}.
FT DOMAIN 4..34
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
SQ SEQUENCE 375 AA; 40407 MW; CABC2918CDCD98B7 CRC64;
MESMLTTSQA ARRLGVKPAT VYAYVSRGLL TSQKVNRASM FDVAEVEALA QRTGARGAVA
AVTDRIRTRI SLQEHDRLYY RGRSAVELSG SRRFEDVAHW LWTGADTTGF EFPEGQEIWM
ALPDSATLTD RIRVAVALAG AGDPLRFDLD RAVTTATALI ADVVESLPLV QPPRGPDIAD
RLWARLSAEP PEPEVLNAAL VLLADHDLAA STLAARVAAS ARAHPYAVVS AGLGAMEGQK
HGTASTIAHR FLLQAAADPV AAVAERLRAG EPIPGFGFGH GVYQHRDPRA DHLLAILRER
GELVADQVIE TLPQTFPNVD LALAQLGLTY KMAPDAGEAI FAVARIVGWI AHAMEEYAEP
GLRFRTLGVY TGDRP
//
