ID A0A0M8WC21_9NOCA Unreviewed; 717 AA.
AC A0A0M8WC21;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:KOV82909.1};
GN ORFNames=ADL03_22970 {ECO:0000313|EMBL:KOV82909.1};
OS Nocardia sp. NRRL S-836.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1519492 {ECO:0000313|EMBL:KOV82909.1, ECO:0000313|Proteomes:UP000037746};
RN [1] {ECO:0000313|Proteomes:UP000037746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-836 {ECO:0000313|Proteomes:UP000037746};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV82909.1}.
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DR EMBL; LGDY01000103; KOV82909.1; -; Genomic_DNA.
DR RefSeq; WP_053735537.1; NZ_LGDY01000103.1.
DR AlphaFoldDB; A0A0M8WC21; -.
DR STRING; 1519492.ADL03_22970; -.
DR PATRIC; fig|1519492.3.peg.4926; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000037746; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037746};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 509..528
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..561
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 573..597
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 618..640
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 652..677
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 212..325
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 717 AA; 73602 MW; C66F0CAB69E85AC0 CRC64;
MAKLLYRLGL GAHRHRLPVV LIWLLVLVGS GVGAFTLGGE TSNSMSIPGQ ESTTALERIQ
QTFGTGETAS ARVVVHAQDK LPAHAKAVTE LVADLGKLDG VSSATNPLDP AKPSVNRDVD
TGYSTVTYDV KPGEVTADQR TALLGAVDKA RATGLTIEVS GTAMQAPPHV GGPTEAIGVV
LALVILALTY GSLVTAGMNL LSAGIGVGIG TLGITITSGF LDLQSTTPIL ASMLGLAVGI
DYALFIINRY RQELRRGADV GHAVATAVGT AGSAVVTAGL TVVIALVGLV IAGIPFLTQM
GVAAAATIVV AVLIAITLVP AVLSMLGRRV LTRKERASTD VEPKDRGVIR GWAGLVTKRR
VTALLLSVVV LGIASIPVAS MDTTLIQKPP AGSTQERADQ LLARGFGEGF NGPIIVLVEG
SDAAATATKA AGPIAKLTDV ALVTPAQPSA DGNSALLTVI PKSGPDTAAT EQLVADLRAE
LAGLDGGKAY VTGATAVSVD VATSLDRALP IYLAVVVGLA LVLLVLVFRS LLVPLVGVLG
FLLTIGASLG ATVAVFQWGW LADAVNLDGT GPLISLTPIL VIGILFGLAM DYQIFLVSRM
HEAHHRGASP LEAITTGFRQ AAPVVVAAAL IMFSVFAGFV PAGEPTVKSI AFALAAGIFV
DAFVVRMILV PAALALIGER AWWLPSWLRW LPELDVEGTA LDAMPAAKKP QETVAVS
//
