ID A0A0M8XJJ3_9ACTN Unreviewed; 501 AA.
AC A0A0M8XJJ3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:KOX07502.1};
GN ORFNames=ADK66_19520 {ECO:0000313|EMBL:KOX07502.1};
OS Micromonospora sp. NRRL B-16802.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1415541 {ECO:0000313|EMBL:KOX07502.1, ECO:0000313|Proteomes:UP000037709};
RN [1] {ECO:0000313|EMBL:KOX07502.1, ECO:0000313|Proteomes:UP000037709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16802 {ECO:0000313|EMBL:KOX07502.1,
RC ECO:0000313|Proteomes:UP000037709};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOX07502.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LGEB01000068; KOX07502.1; -; Genomic_DNA.
DR RefSeq; WP_053657346.1; NZ_LGEB01000068.1.
DR AlphaFoldDB; A0A0M8XJJ3; -.
DR STRING; 1415541.ADK66_19520; -.
DR PATRIC; fig|1415541.3.peg.4088; -.
DR OrthoDB; 3495787at2; -.
DR Proteomes; UP000037709; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07116; ALDH_ACDHII-AcoD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR43111; ALDEHYDE DEHYDROGENASE B-RELATED; 1.
DR PANTHER; PTHR43111:SF1; ALDEHYDE DEHYDROGENASE B-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 23..488
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 257
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 501 AA; 54373 MW; BF5D4EA7299D6AEB CRC64;
MTRYDAPTHW QSRYDHFIGG EYVKPHGGDY FENPTPVTGQ TFTEVARGTA PDVEKALDAA
HGAADAWGRT SVAERALILN RIADRMQDNL ESLAIAESWE NGKPVRETLA ADIPLAIDHF
RYFAGAIRAQ EGSLGELDDD TVAYHFHEPL GVVGQIIPWN FPILMATWKL APALAAGNAV
VLKPAEQTPA SIHYWLSLVA DLLPPGVLNI VNGFGVEAGK PLASSPRVAK VAFTGETTTG
RLIMQYASEN IKPVTLELGG KSPNIFFDDV SAASDDFLDK ALEGFTMFAL NQGEVCTCPS
RALIQQGHYS DFLDAAVART KAIVAGHPLD TDTMIGAQAS NDQLEKILSY LDIGRQEGAK
VLTGGSRADL GGDLSGGYYV EPTIFEGDNS MRIFQEEIFG PVVSVTSFAD LDDAVKIAND
TLYGLGAGVW SRDMNTAYRA GRAIQAGRVW TNCYHAYPAH AAFGGYKQSG IGRENHKMML
EHYQQTKNLL VSYSTKKLGF F
//
