ID A0A0M8ZYD3_9HYME Unreviewed; 854 AA.
AC A0A0M8ZYD3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE SubName: Full=DNA repair protein complementing XP-C cells like protein {ECO:0000313|EMBL:KOX73447.1};
GN ORFNames=WN51_14493 {ECO:0000313|EMBL:KOX73447.1};
OS Melipona quadrifasciata.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Melipona.
OX NCBI_TaxID=166423 {ECO:0000313|EMBL:KOX73447.1, ECO:0000313|Proteomes:UP000053105};
RN [1] {ECO:0000313|EMBL:KOX73447.1, ECO:0000313|Proteomes:UP000053105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0111107301 {ECO:0000313|EMBL:KOX73447.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KOX73447.1};
RA Pan H., Kapheim K.;
RT "The genome of Melipona quadrifasciata.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
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DR EMBL; KQ435798; KOX73447.1; -; Genomic_DNA.
DR STRING; 166423.A0A0M8ZYD3; -.
DR Proteomes; UP000053105; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 3.10.620.30; -; 1.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR018026; DNA_repair_Rad4-like.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR NCBIfam; TIGR00605; rad4; 1.
DR PANTHER; PTHR12135:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053105}.
FT DOMAIN 595..648
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 650..706
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 713..787
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 322..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 402..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..337
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..423
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 854 AA; 98037 MW; 6243C22DA1A68554 CRC64;
MSGLSEDDSS DSSNEYLVDP EKINLNSSFF TKKNLDDAAV VDKINTDDED TDEDFEDVNQ
TGNIELFTQV LKNLEHSQKF EFNDENAEKK ESHSDHLVLQ KKEAQKVESD MKDVTSSNEI
NELLLQGESS VSSPSKKLSV NGIAKNEEDA EPPNEYTIPK DGVKIILPGT SLMINKKKKG
KPDLKAILRK RLRDTQILVE KVGLLCWLAY GYHLNRQINQ PEIMASVLSL ISASNYPKNR
IDLTYLEKFT KWFKHMFTLE PVESNGNKQI DKETLLKILK EKKISNYKEL VLLYVATLRA
LGLNCRLVIS LCPPHRIYND NPLFKSDNKE SETATKKKTA TTNKSTTTKG RSSKKQKNKK
EVSDKTNVIK NSLEAKKNAN LEAKKRAAEI LXXXXEILHS KVQNKTVKKS NTKSKEKKDV
AQPAVQEKSL SNLRQLRSHK VNTTKVMNST DISSKTDDTK SKYYIEDSTD SETEFQPKPK
LKKKKDKEEK LRQDIWAEIY LESEESWICA SVMDEKIHCV TEVYKRATKP VLYVVAWNSE
GLLKDVTRRY CAQWLTVTRK QRVDEKWWSE TLSYWKEKNT AISRAEDEML LQKELEQPLP
KTISEIKGHP LYVIQRHLLK FEVLYPPDCV PLGHTSTGEA IYSRHCVHTV RSRETWLKQA
RVVKPNEEPY KIVKSRPKYD KLSGLKIKDS PLEVFGEWQT KEYEPPVAKD GIVPRNEYGN
VDLFKQCMLP KGTVHINLPG LNRIARKLNI DCAPAVVGFN FGGMGAVPAI EGYVVCSEYE
DTLREAWEAE QAEAVKRNKE KQEKRIYGNW KRLIQGLLIR ERLAARYEFS QETKSITKKR
AKDKKTSTKK TKVF
//
