ID   A0A0M9XAW0_9ACTN        Unreviewed;       905 AA.
AC   A0A0M9XAW0;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
DE   Flags: Fragment;
GN   ORFNames=ADK41_02410 {ECO:0000313|EMBL:KOT46217.1};
OS   Streptomyces caelestis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=36816 {ECO:0000313|EMBL:KOT46217.1, ECO:0000313|Proteomes:UP000037773};
RN   [1] {ECO:0000313|EMBL:KOT46217.1, ECO:0000313|Proteomes:UP000037773}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-24567 {ECO:0000313|EMBL:KOT46217.1,
RC   ECO:0000313|Proteomes:UP000037773};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOT46217.1}.
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DR   EMBL; LGCN01000003; KOT46217.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M9XAW0; -.
DR   PATRIC; fig|36816.3.peg.519; -.
DR   OrthoDB; 2472181at2; -.
DR   Proteomes; UP000037773; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR   GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR   GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR   CDD; cd19540; LCL_NRPS-like; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.980; -; 2.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   Pfam; PF00668; Condensation; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS50075; CARRIER; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037773}.
FT   DOMAIN          99..174
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KOT46217.1"
FT   NON_TER         905
FT                   /evidence="ECO:0000313|EMBL:KOT46217.1"
SQ   SEQUENCE   905 AA;  97189 MW;  3E79FDA2BBB1FBCD CRC64;
     IEPGEIESAL VVHPSVAQAA VVVREDRPGD KRLIAYVVAA GDGRVDTDAL RRHAGAALPE
     YMVPAAFVEL DLLPLTANGK LDRRALPEPR LGTGPGGRQG RTPVEEVLCG LFADALGLPA
     VSIDDDFFRL GGHSLLATRL VSRVRRTLGA RVSVRDLFRQ PTVARLAVFI AEGADADRRP
     ALVAGERPER VPLSAAQRRL WFLDQMEGPS ATYNIPLAVR LTGALDADAL HLALSDVVAR
     HEALRTVFPA EQGTPYQRVL PAEEARPALA LIPATREALP TVLRDLSATT FDLARELPLR
     ADLLRVEDDE HVLLLVTHHI ASDGWSTTPL MRDLAAAYTA RVEGAAPGWE PLPVQYADYA
     LWQQALLAAD EERQLDHWRQ ALEGLPEEVT LPADRARPAT ASYRGASLTV RCPAGLHASL
     TRLARESGTT LFMVAQAATA ALLARSGAGG DIPIGSPVAG RGEEALEDLV GFFVNTLVLR
     TDVSGDPTFR ELLDRVRTTD LAAWSHQDVP FDRLVEALNP ERSAARHPLF QVMLSVTDAA
     DPVPRLPGLH ADAEFTTLDI AKFDLTFTFH EHRAPDGGPA GLGITVEYAT DLYDPATVSA
     VTARLVRLLR AAADTPDTPI GALDVLADDE RARLLDTWHG TRRVRPAAAL PELFAGQAAR
     TPDAVALTHG AQRLTYAELD RRANRLAHRL IAEGVRPGSR VALFQERSPE AVVAILAVVK
     AGAVYVPLDT RYPKDRIDLI VRMSGAEVFL TDRDPSGLEL PDGARALSVT DPAGSYAGTA
     PEVTVHPDQL AYVMFTSGST GVPKGVAVTH RNVTELAADD RFTGGAHRRV LLHSPLAFDA
     TTYELWAPLL SGGTLVVAPP GLLDAAALTR VLAEGSVTGL WLTVGLFRLV AEEDPAAFAG
     LREVW
//