ID A0A0M9ZK52_9ACTN Unreviewed; 556 AA.
AC A0A0M9ZK52;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=AMP-dependent synthetase {ECO:0000313|EMBL:KOV60916.1};
GN ORFNames=ADL01_32520 {ECO:0000313|EMBL:KOV60916.1};
OS Streptomyces sp. NRRL WC-3618.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519490 {ECO:0000313|EMBL:KOV60916.1, ECO:0000313|Proteomes:UP000037738};
RN [1] {ECO:0000313|EMBL:KOV60916.1, ECO:0000313|Proteomes:UP000037738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL WC-3618 {ECO:0000313|EMBL:KOV60916.1,
RC ECO:0000313|Proteomes:UP000037738};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV60916.1}.
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DR EMBL; LGDW01000457; KOV60916.1; -; Genomic_DNA.
DR RefSeq; WP_053745595.1; NZ_LGDW01000457.1.
DR AlphaFoldDB; A0A0M9ZK52; -.
DR PATRIC; fig|1519490.3.peg.7084; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000037738; Unassembled WGS sequence.
DR GO; GO:0016878; F:acid-thiol ligase activity; IEA:UniProt.
DR GO; GO:0016405; F:CoA-ligase activity; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Reference proteome {ECO:0000313|Proteomes:UP000037738}.
FT DOMAIN 50..405
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 455..532
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 556 AA; 61492 MW; AB8177184DAAC1FD CRC64;
MTTVTEHFRE ARDFLLTHRE DYATAYEGFR WPRPERFNWA LDWFDVIAEG NDRTALHIVE
EDGSEARVSF AEMSARSDRV ANWLRGLGIR QEDRVLVMLG NQVELWETAL AAMKIGAVVI
PATPLLGPAD LRDRVERGRI AHVLVRAEDT GKFDEVPGPY TRIAVGGAPE GWRPYEDAYD
APAQFTPDGP THADDPLMLY FTSGTTARPK LVEHTHASYP IGHLATMYWI GLKPGDVHLN
ISSPGWAKHA WSNLFAPWNA EATVFIHNYT RFDAGRLMAE MDRAGVTSFC APPTVWRLLI
QADLTQLRTP PREVVAAGEP LNPEVIEQVR RFWGVTIRDG FGQTETAVQV SNSPGQPLKT
GSMGRPSPGY QVVLLDPVSG EPGATEGEIA LDLSTHPVGV MTGYHGDADR TAEAMAGGFY
RTGDIGSRDT DGYITYVGRA DDVFKASDYK ISPFELESAL LEHEAVAEAA VVPAPDALRL
AVPKAYIVLA AGWEPGPDTA KVLFEHSREV LAPYKRLRRL EFADLPKTVS GKIRRIELRE
ATAAGSADEY REEDFR
//
