ID A0A0N0A1V4_9NOCA Unreviewed; 337 AA.
AC A0A0N0A1V4;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KOV85352.1};
GN ORFNames=ADL03_14560 {ECO:0000313|EMBL:KOV85352.1};
OS Nocardia sp. NRRL S-836.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1519492 {ECO:0000313|EMBL:KOV85352.1, ECO:0000313|Proteomes:UP000037746};
RN [1] {ECO:0000313|Proteomes:UP000037746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-836 {ECO:0000313|Proteomes:UP000037746};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV85352.1}.
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DR EMBL; LGDY01000091; KOV85352.1; -; Genomic_DNA.
DR RefSeq; WP_053733874.1; NZ_LGDY01000091.1.
DR AlphaFoldDB; A0A0N0A1V4; -.
DR STRING; 1519492.ADL03_14560; -.
DR PATRIC; fig|1519492.3.peg.3099; -.
DR OrthoDB; 37081at2; -.
DR Proteomes; UP000037746; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037746};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..60
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT DOMAIN 7..50
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 337 AA; 35447 MW; 1D599BF7F1ED9D31 CRC64;
MSRSAPTLED VARVAGVSRA TVSRVVNGTR NVDPQLQETV RNAIEQTGYS PNRAARSLVT
RRTGTVALVI SGAGGGSDVF TDPFFGRVTA GVVDCLRPHG VHPVLMLADS EQARTEVVEF
LRQGSADGAL LVTTHPADPL PARLMAAGVP AVLYARPGTP TPVSYVDLDH RAGGRLAADH
LVAGGRTNVV TISGPLDVLA SQDRLAGFRD AMARHGFPYV PSAEGGFTAQ SGEAAMNRLL
TEHPDLDGVF AANDLMAQAA VFVVQAHGLR VPDDVAVVGF DDSAPALACR PQLTTVRQPV
EEMAAEMAEL LLADLEEPGQ RPRSVIFEPE LVVRASA
//
