ID   A0A0N0ALP0_9ACTN        Unreviewed;      1000 AA.
AC   A0A0N0ALP0;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=HTH luxR-type domain-containing protein {ECO:0000259|PROSITE:PS50043};
GN   ORFNames=ADL05_17775 {ECO:0000313|EMBL:KOX14134.1};
OS   Nocardiopsis sp. NRRL B-16309.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Nocardiopsaceae; Nocardiopsis.
OX   NCBI_TaxID=1519494 {ECO:0000313|EMBL:KOX14134.1, ECO:0000313|Proteomes:UP000037694};
RN   [1] {ECO:0000313|Proteomes:UP000037694}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-16309 {ECO:0000313|Proteomes:UP000037694};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOX14134.1}.
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DR   EMBL; LGEC01000080; KOX14134.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N0ALP0; -.
DR   STRING; 1519494.ADL05_17775; -.
DR   PATRIC; fig|1519494.3.peg.3856; -.
DR   Proteomes; UP000037694; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037694}.
FT   DOMAIN          919..984
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
FT   REGION          505..552
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          902..923
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          980..1000
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        980..994
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1000 AA;  105096 MW;  D4AAB543D37BE21E CRC64;
     MRGRDEETAK VDAVLAAARS GRSGALVLRG EAGIGKSALL DHAERGAAAT GTRVLRGAGV
     ESESDLPYAG LHLLLGRAME HVDALPSPQA RALRGALGLA DSASPSRFLV GLAVLTLLAE
     LAATGPVLCL VDDAHWLDRE SAEALLFATR RLEAEGVAVL LAVREPHAPL LATPHIDELR
     LRRLPRTDAE ALLREHAVGL PRQVRGQVLA DAAGNPLALL TLAAAQRDGY SSTRMGVSGR
     IQDTFADQVA ALPERTRALL LVAAADDSAD AATVLRAARD LDARPDDLGP AERRGLLRVA
     ENRVEFTHPL IRAAAYESAA SEDRARAHRA LAGVYADRPE AADRRARHLA AATPTADEEV
     AALLEAAAER ARARGGLSAV ATAYERAAAL SPEPADRRRR TIAAAEAAAY AGDPARAAEL
     LVGVTGTDDT GQRVTVARLH SMLAAAEGRA DASYRVLFAA ALDAEAQEES GAVVGAEVTA
     GDAGTNGIAE ANEDDATARN IRTTAATGSA GDAGDTGDDA TPAATGAAVS DVPTGTAGAF
     GSAMGTGDRA GAPRTAESGR LLLEAVRAAW VANDFDCVAR IGDHAARHPG GAPARTLARA
     ALATNQLEQG RTAEGVAALR ASLDGHDALV DPTLNDRVLY ARLHLIAGDH DAAYRAAVDL
     ESECRAQGAL AVLPQVQVVL ARTQFFHGRH RDARATVEDG LRTATDACQP TPLAELAAIG
     AELAAVRGDS ELCRALAAEP LERGVAPASV HAAVALSLLD LGQGRPEEAL VRLESVVEGT
     RPMGIVGNLP LLVEAAFRLG RTDRAIEAAD RYTAWATALD RPWAVSSALR CRALLDGSED
     AYRGALALDA APFEQARTRL LFGEWLRRAR RATEAREQLH LAADAFRRWD ARPWEERARA
     ELRATGETRA TDTLARDRSE DPLDRLTPQE LQVVRLAATG LTNRDIGAQL FLSPRTVGHH
     LYKAYPKLGV ASRAELGALG LHRDQERRRS DGEQAEAPVG
//