ID A0A0N0ASK6_9ACTN Unreviewed; 760 AA.
AC A0A0N0ASK6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Molybdopterin oxidoreductase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ADL06_22900 {ECO:0000313|EMBL:KOX23014.1};
OS Streptomyces sp. NRRL F-6491.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519495 {ECO:0000313|EMBL:KOX23014.1, ECO:0000313|Proteomes:UP000037743};
RN [1] {ECO:0000313|EMBL:KOX23014.1, ECO:0000313|Proteomes:UP000037743}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-6491 {ECO:0000313|EMBL:KOX23014.1,
RC ECO:0000313|Proteomes:UP000037743};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOX23014.1}.
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DR EMBL; LGEE01000231; KOX23014.1; -; Genomic_DNA.
DR RefSeq; WP_053650191.1; NZ_LGEE01000231.1.
DR AlphaFoldDB; A0A0N0ASK6; -.
DR PATRIC; fig|1519495.3.peg.4888; -.
DR OrthoDB; 5287431at2; -.
DR Proteomes; UP000037743; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR CDD; cd02787; MopB_CT_ydeP; 1.
DR CDD; cd02767; MopB_ydeP; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037951; MopB_CT_YdeP.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR InterPro; IPR041953; YdeP_MopB.
DR NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 120..488
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT DOMAIN 643..750
FT /note="Molybdopterin dinucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF01568"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 760 AA; 82615 MW; A8A39750E2B7A39B CRC64;
MVSKPPAGDP VQDAPQVTPP QHAAAGLPAV GHTLRIAREQ MGSLRTARTL LKVNQKDGFD
CPGCAWPEED KRHVAEFCEN GAKAVAEEAT LRRVTPEFFA AHPVADLAER SGYWLGQQGR
ITQPMLLPEG GDRYEPVTWE RAFAILAEEL RALDSPDEAL FYTSGRTSNE AAFLLQLFAR
EFGTNNLPDC SNMCHESSGS ALTETIGVGK GSVSLEDLHR ADLIVVAGQN PGTNHPRMLS
ALEKAKAAGA RIISVNPLPE AGLERFKNPQ TPRGMLRGAA LTDLFLQIRI GGDQALFRLL
NKLVLATPGA VDEEFVREHT HGYEEFAAAA GEADWAETLA ATGLERSEIE RALEMVLASE
RTIVCWAMGL TQHKHSVPTI REVVNLLLLR GNIGRPGAGV CPVRGHSNVQ GDRTMGIFER
PAPAFLDALD KEFGIVSPRH HGFDVVRSIQ ALRDGEAKVF FAMGGNFVGA TPDTEVTEAA
MRRARLTVHV STKLNRSHAV TGTRALILPT LGRTDKDVQK GGRQFVTVED SMSLVHASRG
NLPPASPHLL SEPAIVARLA RAVLGDRSAT PWEEFEADYA RIRDRIARVV PGFEDFNARL
AADPGGFALP HAPRDERRFP TRTGKANFTA APVEYPRVPE GRLLLQTLRS HDQYNTTIYG
LDDRYRGIKG GRRVVLVHPE DAAAHGLADG AYADLVSEWT DGVERRAPGF RVVHYPTARG
CAAAYYPETN VLVPLESTAD VSNTPASKSV IVRLEQSPST
//
