ID A0A0N0BFL0_9HYME Unreviewed; 525 AA.
AC A0A0N0BFL0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Pituitary homeobox 2 {ECO:0000313|EMBL:KOX73241.1};
GN ORFNames=WN51_00352 {ECO:0000313|EMBL:KOX73241.1};
OS Melipona quadrifasciata.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Melipona.
OX NCBI_TaxID=166423 {ECO:0000313|EMBL:KOX73241.1, ECO:0000313|Proteomes:UP000053105};
RN [1] {ECO:0000313|EMBL:KOX73241.1, ECO:0000313|Proteomes:UP000053105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0111107301 {ECO:0000313|EMBL:KOX73241.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KOX73241.1};
RA Pan H., Kapheim K.;
RT "The genome of Melipona quadrifasciata.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the paired homeobox family. Bicoid subfamily.
CC {ECO:0000256|ARBA:ARBA00006503}.
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DR EMBL; KQ435801; KOX73241.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N0BFL0; -.
DR STRING; 166423.A0A0N0BFL0; -.
DR OrthoDB; 5395268at2759; -.
DR Proteomes; UP000053105; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR45882; PITUITARY HOMEOBOX HOMOLOG PTX1; 1.
DR PANTHER; PTHR45882:SF3; PITUITARY HOMEOBOX HOMOLOG PTX1; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Reference proteome {ECO:0000313|Proteomes:UP000053105}.
FT DOMAIN 472..519
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 474..520
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 386..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..440
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 525 AA; 58951 MW; 0385D207DA3BD91E CRC64;
MATLNTSKFL VTKTTFLSQK YGQSPRFKNS LRTEIMKSLK NVSESSVKRD QLVLVKCVLE
QSLERILKQV LREIRFGASF WRRNFGVDFR RNFNTANIVT QRYNLQVANV APKLEIYNER
LMERGSGGGG SLELAGGGGG GGGNTDLCLQ DLVTGSTTGL SVQHHQHSAA AASMAGLHGD
HLQGTMHHHD LHGNSHHNAS MLHDSSHQLH EPLEKLKRDA VKRRCQVLEH EIRRQNQNST
DDNGVNSSAT FSYKNSKTRN STLIPNYLKP FFTLVCIFIL HYNNTSQFLY KLQLNTAAVK
DVCYESPSNI TLEKILDDRE KEKKSPDPFS QMDPNTSNFC LFLRFNHRRR LRRRGQTMLQ
EGVMRFAVWA QGDFRDEVTG GLARLDLTGH GAHTPGGSNP STPGATPTTP SGGFSTAQPR
SRTNTTHRPD IRKDVATPTE VKHELGTSGG VVSPDGVVGV NNADDKDGKK NKRQRRQRTH
FTSQQLQELE ALFMRNRYPD MSTREEIGLF TKLPEPRVRN HIKIV
//
