ID   A0A0N0E3U6_9PSED        Unreviewed;      4337 AA.
AC   A0A0N0E3U6;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Non-ribosomal peptide synthase/amino acid adenylation enzyme {ECO:0000313|EMBL:KPA90510.1};
GN   ORFNames=PF66_02571 {ECO:0000313|EMBL:KPA90510.1};
OS   Pseudomonas fuscovaginae.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=50340 {ECO:0000313|EMBL:KPA90510.1, ECO:0000313|Proteomes:UP000037931};
RN   [1] {ECO:0000313|EMBL:KPA90510.1, ECO:0000313|Proteomes:UP000037931}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IRRI 6609 {ECO:0000313|EMBL:KPA90510.1,
RC   ECO:0000313|Proteomes:UP000037931};
RX   PubMed=26422147;
RA   Quibod I.L., Grande G., Oreiro E.G., Borja F.N., Dossa G.S., Mauleon R.,
RA   Cruz C.V., Oliva R.;
RT   "Rice-Infecting Pseudomonas Genomes Are Highly Accessorized and Harbor
RT   Multiple Putative Virulence Mechanisms to Cause Sheath Brown Rot.";
RL   PLoS ONE 10:E0139256-E0139256(2015).
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPA90510.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JSYZ01000009; KPA90510.1; -; Genomic_DNA.
DR   RefSeq; WP_054062872.1; NZ_JSYZ01000009.1.
DR   STRING; 50340.PF66_02571; -.
DR   PATRIC; fig|50340.43.peg.5958; -.
DR   OrthoDB; 9757559at2; -.
DR   Proteomes; UP000037931; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR   GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   CDD; cd05930; A_NRPS; 1.
DR   CDD; cd17646; A_NRPS_AB3403-like; 1.
DR   CDD; cd17649; A_NRPS_PvdJ-like; 1.
DR   CDD; cd19543; DCL_NRPS; 1.
DR   CDD; cd19534; E_NRPS; 1.
DR   CDD; cd05931; FAAL; 1.
DR   CDD; cd19531; LCL_NRPS-like; 2.
DR   Gene3D; 3.30.300.30; -; 4.
DR   Gene3D; 3.40.50.980; -; 6.
DR   Gene3D; 1.10.1200.10; ACP-like; 3.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 4.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 4.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR040097; FAAL/FAAC.
DR   InterPro; IPR010060; NRPS_synth.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 3.
DR   NCBIfam; TIGR01720; NRPS-para261; 1.
DR   PANTHER; PTHR45398; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR   PANTHER; PTHR45398:SF1; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR   Pfam; PF00501; AMP-binding; 4.
DR   Pfam; PF13193; AMP-binding_C; 3.
DR   Pfam; PF00668; Condensation; 4.
DR   Pfam; PF00550; PP-binding; 4.
DR   SMART; SM00823; PKS_PP; 4.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 4.
DR   SUPFAM; SSF47336; ACP-like; 4.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 8.
DR   PROSITE; PS00455; AMP_BINDING; 3.
DR   PROSITE; PS50075; CARRIER; 4.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 3.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   DOMAIN          582..657
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          1637..1712
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          2708..2782
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          4240..4315
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   4337 AA;  480746 MW;  685699385996958E CRC64;
     MIDAFELPNT LAQALQRRAL QTPDRLALRF LAEDKEQGAV LSYRDLDLRA RTIAAALQAN
     AQLGDRAVLL FPSGPDYVAA FFGCLYAGVI AVPAYPPESS RRHHQERLLS IIADAEPRLV
     LTSADLREPL LQMDELSAAD APRLLCVDTL DSALADNWRD AGVQPDDIAF LQYTSGSTAM
     PKGVQVSHGN LVANEVLIRH GFGIDLNPDD VIVSWLPLYH DMGLIGGLLQ PIFSGVPCVL
     MSPAYFLGRP LRWLEAISEY GGTISGGPDF AYRLCSERVS ETALARLDLS GWRVAYSGSE
     PIRLDTLERF AEKFAPCGFS EQSYFASYGL AEATLFVAGG QRGQGIPALR VDEAALAQNR
     AQPGDGSPIM SCGTSQPEHA VRVVEPASLQ VLGENAVGEV WAAGPSIAHG YWRNPEASAK
     TFVQHEGRTW LRTGDLGFMR EGELFITGRL KDMLIVRGHN LYPQDIEQTI EREVDVVRKG
     RVAAFAVTRD GQDGIGIAAE ISRSVQKILP ADALIKLIRQ AVAEAYQEAP SVVVLLNPGA
     LPKTSSGKLQ RSACRNRLAD GSLDSYALFP DQTAASDEVS ETVVDELQAL IGRIWQEQLQ
     VDKVAADDHF FLLGGNSILA TQVVARLREA LGIELNLRLL FEAPTLGAFA AQVARQQQDG
     GAAQGTIVQL SRSQELPQSL AQNRLWFLWQ LDPQSSAYTI PGALRLRGEL DEAALRNSFE
     RLIERHESLR TRFYERDGQA MQRIDASAAF DLQLIDLGDL PTDQREARAR QIREDAARTQ
     FDLEKGPLLW VTLVRLDDQE HQLLVTMHHI IADGWSLNIL IDEFARLYAA AAQGQVAELA
     PLPLQYADYG SWQRQWLAQG ESRRQLAYWK EQLDGELPRL DLATDHPRSA QKRHSAARLN
     LRLDAALSAA VRQTAQACES TPFMLLLSAF QSLLFRYSGQ RDIRIGVPSA NRPRLETQGL
     IGFFINTLVL RAGLEARLPF VELLAQTRQA TLDAQANQDL PFEQLLEAFP EAREQGLFQV
     MFNHQQRDLG ALRRLPGLLA DELPWHSREA KFDLQLHSEE DRSGRLSLAF DYADELFDEA
     TIARLAEHFV SLLQQVTRQP EQAIGDLQLL TATEREQQAA WGVAPCTPAG EWLPELLNRQ
     AQLTPQRTAL VWDGGRLDFA ELHAQANRLA HYLRDKGVGP DVRVAIAAER SPQLLIGLLA
     IIKAGGAYVP LDPDYPRERL AYMLVDSGAE LLLTQSHLLD SLPVAAGVSA VAMDLLKLDN
     WPSQAPGLHL HGDNLAYVIY TSGSTGQPKG VGNTHAALAE RLQWMQATYA LDAGDVLMQK
     APISFDVSVW ECFWPLITGC QLVIAGPGEH RDPYRIAQLV QTFGVTTLHF VPPLLQLFIN
     EPQVARCASL RRLFCGGEAL PAELRNRVLE QLPQVQLHNR YGPTETAINV THWHCQASDG
     ERSPIGRPLG NVTCRVLDAE LNPLPNGVPG ELCIGGIGLA RGYLGRAGLT AERFVADPLG
     AAGERLYRTG DRARWAADGV LEYLGRLDQQ VKLRGFRVEP EEIEARLLAL EGVTQAVVLV
     RDTLAGAQLI GYYTSPGSRV AEQQQSAALK AALAAELPEY MVPAQLLRLD EMPLSPSGKL
     DRKALPEPQW QVREHIEPVT ALQQQIAAIW REVLGQPQVG LGDDFFALGG HSLLATQIIS
     RTRQACDVEL PLRVLFEAPE LGAFAEQVQQ LQASGRRNQQ AAIGLVDRSQ TVPLSYSQQR
     MWFLWQMEPD SPAYNVGGMA RFTGVLNVAC FEAALQALIQ RHETLRTTFP SRNGVAHQQV
     SAETAVRLAW KDFSTLDREA REQRLQQLAD SEAHQPFNLE TGPLLRACLV KAAEQEHYFV
     LTLHHIVTEG WAMDIFAREL SALYEAFIDQ RPSPLPPLPV QYLDYSVWQR QWLESGERQR
     QLDYWTAQLG NEHPLLELPS DRPRPPVQSH RGELYRFDLS DELAARVRAF NTQQGLTLFM
     TMTAALSVLL YRYSGQTDLR IGAPVANRIR PESEGLIGAF LNTQVLRCQL DGQMSVGELL
     EQVRHTVIEG QSHQDLPFDH LVEALQPPRS AAYNPLFQVM CNVQRWEFQQ SRTLGEMRVE
     YLVNDARATK FDLNLEVTDL DHRLGCCLTY STDLFDEPRI ARMAAHWRNL LEALIGDPQQ
     RLSELPLLQA DEQQALFASL GAEAGEQRLD QCIHQLFRQQ AEARPDAPAL TFAGQTLSYA
     ELNAQANRLA WRLREQGVGP QVRVGLALER SLEMVVGLLA ILKAGGAYVP LDPEYPLDRL
     HYMIADSGVG LLLSHRELLE ALGPLPAGVA QWCLEQDGPA LAGYPAEEPP FISLPQHQAY
     LIYTSGSTGK PKGVVVSHGE IAMHCQAVIR RFDMQPDDCE LHFYSINFDA ATERLLVPLL
     SGARVVLRAQ GQWDAEEICQ LIRQQQVNIL GFTPSYGSQL AQWLATQGQI LPVRMCITGG
     EALTGEHLQR IRAAFQPSLF FNAYGPTETV VMPLASLAPQ QLEEGAGSVP IGTVVGARVA
     YILDADLALV PQGATGELYV GGAGLAVGYH QRPAITAERF VADPFGAEGA RLYRTGDLVR
     QRADGLVEYM GRIDHQVKIR GFRIELGEIE NRLLEHDAIR ETVVLALDAP GGKQLAAYLV
     SDVAAQDDAR QLQLREALKA HLKSQLPDYM VPTHLILLES MPLTANGKLD RRALPAPDPE
     LNRQQYVAPS NELEQHLAGI WREVLNVGQV GLNDNFFELG GDSILSIQVV SRARQLGIHF
     SPRDLFQHQT VQSLAAVATY SERITAEQGL LGGESSLTPI QHWFLDSDIP ERQHWNQALV
     LEPVRALEPR ALEQALAALL EHHDALRLGF TVEAGQWRAE YRVPDQATLL QQVQVTALSQ
     CTALFTEVQR SLDLQHGPLL RALLVDGPQG KQRLLLAIHH LVVDGVSWRV LLEDLQNAYR
     QVLAGEAVQL PAKTSSLRDW ANRLQAYAGS ESLREELALW QAQLAGPALD LPCERPEGGR
     QNRHAETVSV RLDATRTRAL LQQAPSAYRT QVNDLLLTAL ARVICRWTGQ PSALVQLEGH
     GRETLFDEID LTRTVGWFTS AYPVRLTPLN IEEAAGQGDS IKAIKEQLRG VPHKGLGYGV
     LRYLAEPSLR EAMASLPLAP VTFNYLGQFD QSFGDEALFR PLEESAGEAH GAEAPLPNEL
     SIDSQVYGGE LVLRWTFSRE RFDNTTIAEL AEAYLGELGS LVEHCLRDDA GGLTPSDFPL
     ARLTQAQLDT LPVAAAQIED VYPLTPMQEG LLLHTLLEPG TGLYYMQDRY RINSELDPQR
     FAQAWQAVIA RHEALRASFC WNVGEDMLQV IHKPGGTPFE YLDWSAEAEE QQEPRLQHLL
     KTEREAGFDL LREAPFHLRL IKVGEARYWF MMSNHHILID AWCRSLLMND FFEIYTALGE
     GREAQLAPPP RYRDYIGWLQ RRDLAEARRW WKGNLQGFER ATPIPSDRPF LREHAGDSGG
     MVVGDRYTRL DPRDGARLRE LAQQHQLTVN TFAQAAWALV LRRFSGDRDV LFGVTVAGRP
     VEMPQMQRTV GLFINSIALR VKLPEEGAGC SVRDWLHGLL ERNMELREYE YLPLVTIQEQ
     SELPKGQPLF DSLFVFENAP VEVSVLDRAQ SLNATSDSGR THTNFPLTAV CYPGDDLGLH
     LSYDQRYFEA ESVERLLGEF KRLLLALVEG FHGDMDELPL VGAEEREFLL EGCNQSAREY
     PLEHSYVALF EAQVAAHPQR IAATCLDRQL SYEQLNQAAN RLGHALVAAG VVVDQPVALL
     AERGLDLLGM IVGSFKAGAG YLPLDPGLPS QRLSRIIGLS RTPLLVCTAA CRAQAEALLQ
     ELNGERPRLL VWEDVQQGAY PLVNPGIHSG PDNLAYVIYT SGSTGLPKGV MVEQRGMLNN
     QLSKVPYLQL APSDVIAQTA SQSFDISVWQ FLAAPLFGAR VDIVPNAIAH DPQGLLEHVR
     QQRITVLESV PSLIQGMLAL DHISLDGLRW MLPTGEAMPP ELAHQWLLRY PQVGLVNAYG
     PAECSDDVAF FRVDLASTRG SYLPIGTPTD NNRLYLLDGA DELVPLGAVG ELCVAGTGVG
     RGYVGDPLRT AQAFIPNPFG APGERLYRTG DLARRRSDGV LEYVGRIDHQ VKIRGYRIEL
     GEIEARLREQ PEVREAAVGV QEGVNGKHLV GYLVATDSAL GQADCLDRIR QRLRAELPEY
     MVPLHWLWLE RLPLNANGKL DRRLLPALEI GQLQGLDYLA PRNELEQTLA AIWAEVLKVE
     RVGVRDNFFE LGGHSLLATQ IASRVQKTLQ RNVPLRAMFE CSTVEELAGY IDGLQADGIS
     EEKVDRLSDL MAELEGL
//