ID A0A0N0NQM3_9EURO Unreviewed; 355 AA.
AC A0A0N0NQM3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Putative 2-hydroxyacid dehydrogenase {ECO:0000313|EMBL:KPI43869.1};
GN ORFNames=AB675_6520 {ECO:0000313|EMBL:KPI43869.1};
OS Phialophora attinorum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Phialophora.
OX NCBI_TaxID=1664694 {ECO:0000313|EMBL:KPI43869.1, ECO:0000313|Proteomes:UP000038010};
RN [1] {ECO:0000313|EMBL:KPI43869.1, ECO:0000313|Proteomes:UP000038010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 131958 {ECO:0000313|EMBL:KPI43869.1,
RC ECO:0000313|Proteomes:UP000038010};
RA Moreno L.F., Stielow B.J., de Hoog S., Vicente V.A., Weiss V.A.,
RA de Vries M., Cruz L.M., Souza E.M.;
RT "Draft genome of the ant-associated black yeast Phialophora attae CBS
RT 131958.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI43869.1}.
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DR EMBL; LFJN01000004; KPI43869.1; -; Genomic_DNA.
DR RefSeq; XP_018003832.1; XM_018146819.1.
DR AlphaFoldDB; A0A0N0NQM3; -.
DR STRING; 1664694.A0A0N0NQM3; -.
DR GeneID; 28738699; -.
DR OrthoDB; 1462550at2759; -.
DR Proteomes; UP000038010; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05198; formate_dh_like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43761:SF1; 2-HACID_DH DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR43761; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630); 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000038010}.
FT DOMAIN 28..334
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 118..310
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 355 AA; 38441 MW; D42E05B0463BC901 CRC64;
MATFKPPPLP TGKDKHHVVV LEAKHVPMPR FDFPHTIDLH PLTKQHEVAE RIKDATIVIA
CVTPVTPADL DVAKHVGCLA IMAVGMAWLN KEEFAKRGVT VTNCAGANVE AVSEHFLALY
FALRKKVVEI DRTVKETDEW RQEGTVTNHW ESRKPPPGCG QEVLGILGYG TIGKRIALLG
KALGFAEILI ADRKGATAEA TKEGRTPFDE VVKRSSTLAV CAPLTKDTVD LISESELQSM
RKEALVINLA RGGIVNEAAL ARALTSGQVA GAATDVLETE PGGPGSTPLL PDLSKGEPAI
PNFVISPHIA WFTQVTIINY QQMLKEGVER WVAGSLIQDG KVIHAVCIHD GKIYR
//
