ID A0A0N0T2J0_9ACTN Unreviewed; 952 AA.
AC A0A0N0T2J0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:KOV69632.1};
GN ORFNames=ADL01_22300 {ECO:0000313|EMBL:KOV69632.1};
OS Streptomyces sp. NRRL WC-3618.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519490 {ECO:0000313|EMBL:KOV69632.1, ECO:0000313|Proteomes:UP000037738};
RN [1] {ECO:0000313|EMBL:KOV69632.1, ECO:0000313|Proteomes:UP000037738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL WC-3618 {ECO:0000313|EMBL:KOV69632.1,
RC ECO:0000313|Proteomes:UP000037738};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV69632.1}.
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DR EMBL; LGDW01000259; KOV69632.1; -; Genomic_DNA.
DR RefSeq; WP_053743784.1; NZ_LGDW01000259.1.
DR AlphaFoldDB; A0A0N0T2J0; -.
DR PATRIC; fig|1519490.3.peg.4872; -.
DR OrthoDB; 3178131at2; -.
DR Proteomes; UP000037738; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000037738}.
FT DOMAIN 878..943
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
FT REGION 636..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 636..650
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 952 AA; 102186 MW; 21FAA450C8E2FA17 CRC64;
MLSASLYERG EALALVAAEA ERARAGTGRL VLLRGATGTG RTALLEAATE QAEAHGMRVL
RVRCSPQRGV ATDTHLPVIE QLLAPVRKLT VPAQRCPPPD ANDVPADVQP AARLWRLLCA
YAAEAPVLVA VDDVHLADEN SRCWLIEAAR RVDRLPILLL VTERSQYDVE PPSAGLVHTL
SPTLVRTHTL APLSLDTATE LVRSAVGDAP EYSQRWVADC VRAGAGNPLL LRALLEDLNA
TTGAPAELPQ TCAALYPGAY PAAVSWWLDC AGAATAEAAR VFAVLEELPQ GPDVELFTET
TGADPCRVRG WLTAMTRLGL LRDDADGRPR YAHPLLRDAV LTGWPAADRQ AAHRAAAEAM
LRRGDPTETV AGQLLRSGPV DEVWATDALL DAATGAVRDD RRDDAVVLLR RALAEPMSAG
RRAEVLTELG SLEFAAVRSS TGIPRLTEAM RLQGLPQYRV QAAVALGTAL ARRGEARAAV
TLLRNLDGQL TDHPDLLHTV QTASALLSDH DQTIREEIYR WLRDTAEHSP QALGPAGRAL
LVRYEATAGL TSADAAMKQV RALLAEPAGP LAEPFLLGTA AAVAQWADEL DEAERLTDRG
LTGQRPTLLH PMHEALLNVR ADIAAARGDY GSLLTEPESW RRREGTGAGD GFRGEESSAE
PAPGTNTGTR PTNADAHILL ALVETGRLDE AGRLADAFDL REAHDSWELN RFLYARGVVR
AASGDPAGAL GDFLECGRRQ SARDVLSPVV TPWRAAAAQC RLDLGHPREA LALAEEELRL
ARVWNTPRLV GRSLRVLGTA TGARHGLDLT DEAVRVLREA SVETELIPAL IARGHQLLAS
GERTRARKSL REATERAERL GAVRLRTTAE AALREGGARR TATTLTASER RIAQLAAAGR
TNTEIAELLH VARRTVETHL TSAYRKLGIR RRGELTVALG RGPGAGQRAG PP
//
