ID A0A0N0T3J0_9ACTN Unreviewed; 600 AA.
AC A0A0N0T3J0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:KOV72598.1};
GN ORFNames=ADL01_19190 {ECO:0000313|EMBL:KOV72598.1};
OS Streptomyces sp. NRRL WC-3618.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519490 {ECO:0000313|EMBL:KOV72598.1, ECO:0000313|Proteomes:UP000037738};
RN [1] {ECO:0000313|EMBL:KOV72598.1, ECO:0000313|Proteomes:UP000037738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL WC-3618 {ECO:0000313|EMBL:KOV72598.1,
RC ECO:0000313|Proteomes:UP000037738};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV72598.1}.
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DR EMBL; LGDW01000197; KOV72598.1; -; Genomic_DNA.
DR RefSeq; WP_053743225.1; NZ_LGDW01000197.1.
DR AlphaFoldDB; A0A0N0T3J0; -.
DR PATRIC; fig|1519490.3.peg.4190; -.
DR OrthoDB; 1550386at2; -.
DR Proteomes; UP000037738; Unassembled WGS sequence.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR CDD; cd01651; RT_G2_intron; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR030931; Group_II_RT_mat.
DR InterPro; IPR013597; Mat_intron_G2.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR025960; RVT_N.
DR NCBIfam; TIGR04416; group_II_RT_mat; 1.
DR PANTHER; PTHR34047:SF8; GROUP II INTRON-ASSOCIATED OPEN READING FRAME; 1.
DR PANTHER; PTHR34047; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF08388; GIIM; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13655; RVT_N; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:KOV72598.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037738};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:KOV72598.1};
KW Transferase {ECO:0000313|EMBL:KOV72598.1}.
FT DOMAIN 109..349
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 600 AA; 67551 MW; 2C814C923EF2F3E6 CRC64;
MTAATAPKDK LDAPAPAGVN GPEGGFVDWP SIDWDQAEKD VRRLRQRIFT ASKEGDLAKV
RNLQKLMLRS LSNTLVSVRR VTEINAGRKT AGIDDQVVLT ALGKSELVRF IQQRGSNWQA
RAVRRVFIPK AGGRKRRPLG IPVIVDRAHQ ARVSAALEPE WEARFEARSY GFRPGRGCHD
AIGVIFNTLS GKNPQRVWIL DADLAAAFDR IDHDQLLAGL GTFPARGLVR QWLKAGVVER
GRFTPTEEGT PQGGVISPVL LNIALHGMEM AAGVRYHPSG RRAGEIMPNA PVLVRYADDL
VAMCHSRAAA EQVKARLAEW LAPRGLVFNE DKTQIVHAET GFDFLGFNVR RYRSGKLLIK
PSKAAVKRIR GRLREEIRAL RGAEPAAVLR TLNPIVRGWA AYYRTVVSKE VFASLDAYLW
QLTYRWALPR HPKKPRRWIM KRYFGRFNPA RQDNWVFGDR GSGAYLVRFA WTKIIRHQLV
RAGASPDDPA LADYWADRRR KGAPLPLDRA TMRLLKTQAG RCHRCGQLLL HADRSPQSPR
EWEQWLRTTR KAIKTQHIAY QGTKTPDGIQ LRLTHASCRQ RLYADGREET LHTGEPLGLA
//
