ID A0A0N0TTJ2_9PSEU Unreviewed; 334 AA.
AC A0A0N0TTJ2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KOX27483.1};
GN ORFNames=ADK67_13605 {ECO:0000313|EMBL:KOX27483.1};
OS Saccharothrix sp. NRRL B-16348.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1415542 {ECO:0000313|EMBL:KOX27483.1, ECO:0000313|Proteomes:UP000037722};
RN [1] {ECO:0000313|EMBL:KOX27483.1, ECO:0000313|Proteomes:UP000037722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16348 {ECO:0000313|EMBL:KOX27483.1,
RC ECO:0000313|Proteomes:UP000037722};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOX27483.1}.
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DR EMBL; LGED01000125; KOX27483.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N0TTJ2; -.
DR STRING; 1415542.ADK67_13605; -.
DR PATRIC; fig|1415542.3.peg.2961; -.
DR Proteomes; UP000037722; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 9..63
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT DOMAIN 10..53
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 334 AA; 35161 MW; 1117988C32DD2119 CRC64;
MPEECPVRVT IAEVAQRAQV SKATVSRVLN GKPDVDAATA ARVRQVIADV GYVPSARAVG
LARGRARTVG MLVPSLTWPW TGEVVQGAVD ELEAEGYGLL LYTVNRGAES LTQFASHVSA
KAFDGLLVIE PPDTLSYIET LHDQGLPVVM IDDRGSRPGF PSVGTTNREG AQAAAQHLVA
AGRTGFAVVT GPANFGCVRE RLDGFLDALG DAGVHVDPRL VVEGDFGTDR GAVATEKLMA
TGLRFDAVFA QNDLSALGVI RALNAAGRKV PDDVAVVGFD DIPIAAHAEL TTVRQPMREM
GEAAARLLLA RLEGAPPTRE PVVLPTTFVA RRSG
//
