ID A0A0N1BC62_9PROT Unreviewed; 704 AA.
AC A0A0N1BC62;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=prolyl oligopeptidase {ECO:0000256|ARBA:ARBA00011897};
DE EC=3.4.21.26 {ECO:0000256|ARBA:ARBA00011897};
GN ORFNames=IP88_09745 {ECO:0000313|EMBL:KPF73012.1};
OS alpha proteobacterium AAP81b.
OC Bacteria; Pseudomonadota; Alphaproteobacteria.
OX NCBI_TaxID=1523432 {ECO:0000313|EMBL:KPF73012.1, ECO:0000313|Proteomes:UP000037971};
RN [1] {ECO:0000313|EMBL:KPF73012.1, ECO:0000313|Proteomes:UP000037971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AAP81b {ECO:0000313|EMBL:KPF73012.1,
RC ECO:0000313|Proteomes:UP000037971};
RA Zeng Y., Feng F., Liu Y., Koblizek M.;
RT "Novel Diversity of Limnic Aerobic Anoxygenic Phototrophic Bacteria as
RT Revealed by High-throughput Strain Identification and Genome Sequencing.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of Pro-|-Xaa >> Ala-|-Xaa in oligopeptides.;
CC EC=3.4.21.26; Evidence={ECO:0000256|ARBA:ARBA00001070};
CC -!- SIMILARITY: Belongs to the peptidase S9A family.
CC {ECO:0000256|ARBA:ARBA00005228}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPF73012.1}.
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DR EMBL; LJHX01000092; KPF73012.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1BC62; -.
DR STRING; 1523432.IP88_09745; -.
DR PATRIC; fig|1523432.3.peg.3336; -.
DR Proteomes; UP000037971; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.130.10.120; Prolyl oligopeptidase, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002471; Pept_S9_AS.
DR InterPro; IPR023302; Pept_S9A_N.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002470; Peptidase_S9A.
DR PANTHER; PTHR42881; PROLYL ENDOPEPTIDASE; 1.
DR PANTHER; PTHR42881:SF2; PROLYL ENDOPEPTIDASE; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR Pfam; PF02897; Peptidase_S9_N; 1.
DR PRINTS; PR00862; PROLIGOPTASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF50993; Peptidase/esterase 'gauge' domain; 1.
DR PROSITE; PS00708; PRO_ENDOPEP_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000037971};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..704
FT /note="prolyl oligopeptidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005866810"
FT DOMAIN 26..429
FT /note="Peptidase S9A N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02897"
FT DOMAIN 491..699
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
SQ SEQUENCE 704 AA; 76413 MW; 3C26361981127E62 CRC64;
MMKPLPIVVV ALMSLTTPAA AAPAYPPTVR GADVEARHGI SAPDPYRWLE ADVRKEPRVA
DWVAAQNQVT DAYLASLPKR EAIRARLTQL FDYERIRLPV ARAGKLFFRR NSGLQNQDVL
YVEEAGVGAA SRRQLIDPNV WSKDGATALA EWAPSDDGRF IAYAVQDGGT DWRTVRVLDV
AAGRVLDDKL DWVKFSPLAY GKDGFFYARY PEQAGGPDFQ SEVQNHAIWF HKVGTPQSAD
VKVFATPDHP GWYHDAEVSA DGRWLIIRSS TGSDDSYEVR ARDLGRPDSP LITLVAERTD
DWRFAGNRGE ELFFVTNRDA PRYRVVALDA IARRAPRVVV AEGGDTLTGA SLVGDQLLVT
ALKDARTEVR RYAADGTPAG TVPLPGLGTA SGFEASHDGS TTYFTFTSYN APTTIYRYDA
AANAVSVWAA PKVAFDPADY VVEQRFFTSK DGTRVPMFVA HKKGLKLPAP TLMYGYGGFN
INVLPAFQVD ALAWMEMGGV YAEVTLRGGG EYGAAWHDAG RRFKKQNVFD DFIGAGEALI
AAGITRKGGL AIQGGSNGGL LVGAVVNQRP DLFAAALPAV GVMDMLRFPL FTEGRTWTDD
YGDPADPAAF KNLLAYSPYH NIVAGKDYPA ILVTTADTDD RVVPGHSFKY VSALQAAAIG
DRPHLIRIET RAGHGSGKPT TKVIAEAADL WAFAGYWTGL TTAP
//
